Administrative Dose given Drug Purity Calculator

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✖The Effective Dose is a dose or concentration of a drug that produces a biological response.ⓘ Effective Dose [D_e]			+10% -10%
✖The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.ⓘ Drug Purity [Q]			+10% -10%
✖The Bioavailability is the systemically available fraction of a drug.ⓘ Bioavailability [B]			+10% -10%

✖Administered Dose is the amount of drug administered for a pharmacological response.ⓘ Administrative Dose given Drug Purity [D_a]

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Formula

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Administrative Dose given Drug Purity

Formula

`"D"_{"a"} = "D"_{"e"}/("Q"*"B")`

Example

`"0.006377µg"="5.5µg"/("69"*"12.5")`

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Administrative Dose given Drug Purity Solution

STEP 0: Pre-Calculation Summary

Formula Used

Administered Dose = Effective Dose/(Drug Purity*Bioavailability)
D_a = D_e/(Q*B)
This formula uses 4 Variables

Variables Used

Administered Dose - (Measured in Kilogram) - Administered Dose is the amount of drug administered for a pharmacological response.
Effective Dose - (Measured in Kilogram) - The Effective Dose is a dose or concentration of a drug that produces a biological response.
Drug Purity - The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.
Bioavailability - The Bioavailability is the systemically available fraction of a drug.

STEP 1: Convert Input(s) to Base Unit

Effective Dose: 5.5 Microgram --> 5.5E-09 Kilogram (Check conversion here)
Drug Purity: 69 --> No Conversion Required
Bioavailability: 12.5 --> No Conversion Required

STEP 2: Evaluate Formula

Substituting Input Values in Formula

D_a = D_e/(Q*B) --> 5.5E-09/(69*12.5)

Evaluating ... ...

D_a = 6.3768115942029E-12

STEP 3: Convert Result to Output's Unit

6.3768115942029E-12 Kilogram -->0.0063768115942029 Microgram (Check conversion here)

FINAL ANSWER

0.0063768115942029 ≈ 0.006377 Microgram <-- Administered Dose

(Calculation completed in 00.004 seconds)

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Created by Prashant Singh

K J Somaiya College of science (K J Somaiya), Mumbai

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< 25 Dose Calculators

Dose of drug administered orally

Go Dose Non-Intravenous = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Bioavailability of Drug)

Dose of drug administered intravenous

Go Dose Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Area under Curve Non-Intravenous

Dose of A type drug

Go Dose Type A = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Relative Bioavailability)

Dose of B type drug

Go Dose Type B = (Relative Bioavailability*Dose Type A)*(Area under curve Dosage B/Area under curve Dosage A)

Administrative dose given rate of administration and dosing interval

Go Administered Dose = (Drug Rate of Administration*Dosing Interval)/(Bioavailability*Drug Purity)

Previous Rate of Drug Dose given Revised Dose

Go Previous Rate of Dose = (Revised Dose*Measured Steady State Concentration Plasma)/(Target Steady State Plasma Concentration)

Dosing interval given rate of administration

Go Dosing Interval = (Administered Dose*Bioavailability*Drug Purity)/Drug Rate of Administration

Revised Dose

Go Revised Dose = Previous Rate of Dose*Target Steady State Plasma Concentration/Measured Steady State Concentration Plasma

Loading Dose

Go Loading Dose = (Target Plasma Concentration*Volume Of Distribution dose)/Bioavailability Of drug dose

Maintenance Dose

Go Maintenance Dose = Drug Clearance*Target Plasma Concentration/Bioavailability Of drug dose

Dose given volume of distribution and area under curve

Go Dose = Volume of Distribution*Elimination Rate Constant*Area Under Curve

Administrative Dose given Drug Purity

Go Administered Dose = Effective Dose/(Drug Purity*Bioavailability)

Effective dose given drug purity

Go Effective Dose = Drug Purity*Bioavailability*Administered Dose

Adult Dose of Drug by Clark's Equation in Micrograms

Go Adult Dose = Pediatric Dosage/(Weight of Patient in microgram/68)

Clark's Equation of Dosage in Microgram

Go Pediatric Dosage = Adult Dose*(Weight of Patient in microgram/68)

Dosing interval given average plasma concentration

Go Dosing Interval = Area Under Curve/Average Plasma Concentration

Adult Dose of Drug by Clark's Equation

Go Adult Dose = Pediatric Dosage/(Weight of Patient/150)

Weight of Patient by Clark's equation

Go Weight of Patient = (Pediatric Dosage/Adult Dose)*150

Clark's Equation of Dosage

Go Pediatric Dosage = Adult Dose*(Weight of Patient/150)

Weight of Patient in Kilograms by Clark's equation

Go Weight of Patient = (Pediatric Dosage/Adult Dose)*68

Amount of drug administered given apparent volume

Go Dose = Volume of Distribution*Concentration of Drug

Amount of drug in given volume of plasma

Go Concentration of Drug = Dose/Volume of Distribution

Administrative dose given effective dose and bioavailability

Go Administered Dose = Effective Dose/Bioavailability

Effective dose given bioavailability and administrative dose

Go Effective Dose = Bioavailability*Administered Dose

Amount of drug administered given area under curve

Go Dose = Volume of Plasma Cleared*Area Under Curve

Administrative Dose given Drug Purity Formula

Administered Dose = Effective Dose/(Drug Purity*Bioavailability)
D_a = D_e/(Q*B)

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Administrative Dose given Drug Purity?

Administrative Dose given Drug Purity calculator uses Administered Dose = Effective Dose/(Drug Purity*Bioavailability) to calculate the Administered Dose, The Administrative dose given drug purity formula is defined as the ratio of the effective dose of the drug to the drug purity and bioavailability of the particular drug. Administered Dose is denoted by D_a symbol.

How to calculate Administrative Dose given Drug Purity using this online calculator? To use this online calculator for Administrative Dose given Drug Purity, enter Effective Dose (D_e), Drug Purity (Q) & Bioavailability (B) and hit the calculate button. Here is how the Administrative Dose given Drug Purity calculation can be explained with given input values -> 6.4E+6 = 5.5E-09/(69*12.5).

FAQ

What is Administrative Dose given Drug Purity?

The Administrative dose given drug purity formula is defined as the ratio of the effective dose of the drug to the drug purity and bioavailability of the particular drug and is represented as D_a = D_e/(Q*B) or Administered Dose = Effective Dose/(Drug Purity*Bioavailability). The Effective Dose is a dose or concentration of a drug that produces a biological response, The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present & The Bioavailability is the systemically available fraction of a drug.

How to calculate Administrative Dose given Drug Purity?

The Administrative dose given drug purity formula is defined as the ratio of the effective dose of the drug to the drug purity and bioavailability of the particular drug is calculated using Administered Dose = Effective Dose/(Drug Purity*Bioavailability). To calculate Administrative Dose given Drug Purity, you need Effective Dose (D_e), Drug Purity (Q) & Bioavailability (B). With our tool, you need to enter the respective value for Effective Dose, Drug Purity & Bioavailability and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Administered Dose?

In this formula, Administered Dose uses Effective Dose, Drug Purity & Bioavailability. We can use 2 other way(s) to calculate the same, which is/are as follows -

Administered Dose = Effective Dose/Bioavailability
Administered Dose = (Drug Rate of Administration*Dosing Interval)/(Bioavailability*Drug Purity)

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