Amount of drug administered given apparent volume Solution

STEP 0: Pre-Calculation Summary
Formula Used
Dose = Volume of Distribution*Concentration of Drug
D = Vdis*Css
This formula uses 3 Variables
Variables Used
Dose - (Measured in Mole) - The Dose is the amount of drug administered.
Volume of Distribution - (Measured in Cubic Meter) - The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.
Concentration of Drug - (Measured in Mole per Cubic Meter) - Concentration of Drug is the amount of the drug in a given volume of plasma.
STEP 1: Convert Input(s) to Base Unit
Volume of Distribution: 9 Liter --> 0.009 Cubic Meter (Check conversion here)
Concentration of Drug: 83.3 Mole per Liter --> 83300 Mole per Cubic Meter (Check conversion here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
D = Vdis*Css --> 0.009*83300
Evaluating ... ...
D = 749.7
STEP 3: Convert Result to Output's Unit
749.7 Mole --> No Conversion Required
FINAL ANSWER
749.7 Mole <-- Dose
(Calculation completed in 00.020 seconds)

Credits

Created by Prashant Singh
K J Somaiya College of science (K J Somaiya), Mumbai
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Verified by Prerana Bakli
University of Hawaiʻi at Mānoa (UH Manoa), Hawaii, USA
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25 Dose Calculators

Dose of drug administered orally
Go Dose Non-Intravenous = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Bioavailability of Drug)
Dose of drug administered intravenous
Go Dose Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Area under Curve Non-Intravenous
Dose of A type drug
Go Dose Type A = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Relative Bioavailability)
Dose of B type drug
Go Dose Type B = (Relative Bioavailability*Dose Type A)*(Area under curve Dosage B/Area under curve Dosage A)
Administrative dose given rate of administration and dosing interval
Go Administered Dose = (Drug Rate of Administration*Dosing Interval)/(Bioavailability*Drug Purity)
Previous Rate of Drug Dose given Revised Dose
Go Previous Rate of Dose = (Revised Dose*Measured Steady State Concentration Plasma)/(Target Steady State Plasma Concentration)
Dosing interval given rate of administration
Go Dosing Interval = (Administered Dose*Bioavailability*Drug Purity)/Drug Rate of Administration
Revised Dose
Go Revised Dose = Previous Rate of Dose*Target Steady State Plasma Concentration/Measured Steady State Concentration Plasma
Loading Dose
Go Loading Dose = (Target Plasma Concentration*Volume Of Distribution dose)/Bioavailability Of drug dose
Maintenance Dose
Go Maintenance Dose = Drug Clearance*Target Plasma Concentration/ Bioavailability Of drug dose
Dose given volume of distribution and area under curve
Go Dose = Volume of Distribution*Elimination Rate Constant*Area Under Curve
Administrative Dose given Drug Purity
Go Administered Dose = Effective Dose/(Drug Purity*Bioavailability)
Effective dose given drug purity
Go Effective Dose = Drug Purity*Bioavailability*Administered Dose
Adult Dose of Drug by Clark's Equation in Micrograms
Go Adult Dose = Pediatric Dosage/(Weight of Patient in microgram/68)
Clark's Equation of Dosage in Microgram
Go Pediatric Dosage = Adult Dose*(Weight of Patient in microgram/68)
Dosing interval given average plasma concentration
Go Dosing Interval = Area Under Curve/Average Plasma Concentration
Weight of Patient in Kilograms by Clark's equation
Go Weight of Patient = (Pediatric Dosage/Adult Dose)*68
Adult Dose of Drug by Clark's Equation
Go Adult Dose = Pediatric Dosage/(Weight of Patient/150)
Weight of Patient by Clark's equation
Go Weight of Patient = (Pediatric Dosage/Adult Dose)*150
Clark's Equation of Dosage
Go Pediatric Dosage = Adult Dose*(Weight of Patient/150)
Amount of drug administered given apparent volume
Go Dose = Volume of Distribution*Concentration of Drug
Amount of drug in given volume of plasma
Go Concentration of Drug = Dose/Volume of Distribution
Administrative dose given effective dose and bioavailability
Go Administered Dose = Effective Dose/Bioavailability
Effective dose given bioavailability and administrative dose
Go Effective Dose = Bioavailability*Administered Dose
Amount of drug administered given area under curve
Go Dose = Volume of Plasma Cleared*Area Under Curve

Amount of drug administered given apparent volume Formula

Dose = Volume of Distribution*Concentration of Drug
D = Vdis*Css

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Amount of drug administered given apparent volume?

Amount of drug administered given apparent volume calculator uses Dose = Volume of Distribution*Concentration of Drug to calculate the Dose, The Amount of drug administered given apparent volume formula is defined as the product of the apparent volume of the drug to the concentration of the drug. Dose is denoted by D symbol.

How to calculate Amount of drug administered given apparent volume using this online calculator? To use this online calculator for Amount of drug administered given apparent volume, enter Volume of Distribution (Vdis) & Concentration of Drug (Css) and hit the calculate button. Here is how the Amount of drug administered given apparent volume calculation can be explained with given input values -> 749.7 = 0.009*83300.

FAQ

What is Amount of drug administered given apparent volume?
The Amount of drug administered given apparent volume formula is defined as the product of the apparent volume of the drug to the concentration of the drug and is represented as D = Vdis*Css or Dose = Volume of Distribution*Concentration of Drug. The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body & Concentration of Drug is the amount of the drug in a given volume of plasma.
How to calculate Amount of drug administered given apparent volume?
The Amount of drug administered given apparent volume formula is defined as the product of the apparent volume of the drug to the concentration of the drug is calculated using Dose = Volume of Distribution*Concentration of Drug. To calculate Amount of drug administered given apparent volume, you need Volume of Distribution (Vdis) & Concentration of Drug (Css). With our tool, you need to enter the respective value for Volume of Distribution & Concentration of Drug and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Dose?
In this formula, Dose uses Volume of Distribution & Concentration of Drug. We can use 2 other way(s) to calculate the same, which is/are as follows -
  • Dose = Volume of Plasma Cleared*Area Under Curve
  • Dose = Volume of Distribution*Elimination Rate Constant*Area Under Curve
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