Dosing interval given rate of administration Calculator

⤿

Dose

Area under curve

Bioavailability

Drug Content

Drug Stability

Elimination Rate Constant

Isotonic Solutions

Plasma

Steady state Concentration

Volume of Distribution

Volume of plasma cleared

✖Administered Dose is the amount of drug administered for a pharmacological response.ⓘ Administered Dose [D_a]			+10% -10%
✖The Bioavailability is the systemically available fraction of a drug.ⓘ Bioavailability [B]			+10% -10%
✖The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.ⓘ Drug Purity [Q]			+10% -10%
✖Drug Rate of Administration is the amount of drug administered in a particular interval of time.ⓘ Drug Rate of Administration [V_a]			+10% -10%

✖The Dosing Interval is the time between drug dose administrations.ⓘ Dosing interval given rate of administration [Τ]

⎘ Copy

👎

Formula

✖

Dosing interval given rate of administration

Formula

`"Τ" = ("D"_{"a"}*"B"*"Q")/"V"_{"a"}`

Example

`"0.067083s"=("3.5µg"*"12.5"*"69")/"45mg/s"`

Calculator

LaTeX

Reset

👍

Download Pharmacokinetics Formula PDF PDF Image

Dosing interval given rate of administration Solution

STEP 0: Pre-Calculation Summary

Formula Used

Dosing Interval = (Administered Dose*Bioavailability*Drug Purity)/Drug Rate of Administration
Τ = (D_a*B*Q)/V_a
This formula uses 5 Variables

Variables Used

Dosing Interval - (Measured in Second) - The Dosing Interval is the time between drug dose administrations.
Administered Dose - (Measured in Kilogram) - Administered Dose is the amount of drug administered for a pharmacological response.
Bioavailability - The Bioavailability is the systemically available fraction of a drug.
Drug Purity - The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.
Drug Rate of Administration - (Measured in Kilogram per Second) - Drug Rate of Administration is the amount of drug administered in a particular interval of time.

STEP 1: Convert Input(s) to Base Unit

Administered Dose: 3.5 Microgram --> 3.5E-09 Kilogram (Check conversion here)
Bioavailability: 12.5 --> No Conversion Required
Drug Purity: 69 --> No Conversion Required
Drug Rate of Administration: 45 Milligram per Second --> 4.5E-05 Kilogram per Second (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

Τ = (D_a*B*Q)/V_a --> (3.5E-09*12.5*69)/4.5E-05

Evaluating ... ...

Τ = 0.0670833333333333

STEP 3: Convert Result to Output's Unit

0.0670833333333333 Second --> No Conversion Required

FINAL ANSWER

0.0670833333333333 ≈ 0.067083 Second <-- Dosing Interval

(Calculation completed in 00.004 seconds)

You are here -

Home » Chemistry » Pharmacokinetics » Dose » Dosing interval given rate of administration

Credits

Created by Prashant Singh

K J Somaiya College of science (K J Somaiya), Mumbai

Prashant Singh has created this Calculator and 700+ more calculators!

Verified by Prerana Bakli

University of Hawaiʻi at Mānoa (UH Manoa), Hawaii, USA

Prerana Bakli has verified this Calculator and 1600+ more calculators!

< 25 Dose Calculators

Dose of drug administered orally

Go Dose Non-Intravenous = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Bioavailability of Drug)

Dose of drug administered intravenous

Go Dose Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Area under Curve Non-Intravenous

Dose of A type drug

Go Dose Type A = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Relative Bioavailability)

Dose of B type drug

Go Dose Type B = (Relative Bioavailability*Dose Type A)*(Area under curve Dosage B/Area under curve Dosage A)

Administrative dose given rate of administration and dosing interval

Go Administered Dose = (Drug Rate of Administration*Dosing Interval)/(Bioavailability*Drug Purity)

Previous Rate of Drug Dose given Revised Dose

Go Previous Rate of Dose = (Revised Dose*Measured Steady State Concentration Plasma)/(Target Steady State Plasma Concentration)

Dosing interval given rate of administration

Go Dosing Interval = (Administered Dose*Bioavailability*Drug Purity)/Drug Rate of Administration

Revised Dose

Go Revised Dose = Previous Rate of Dose*Target Steady State Plasma Concentration/Measured Steady State Concentration Plasma

Loading Dose

Go Loading Dose = (Target Plasma Concentration*Volume Of Distribution dose)/Bioavailability Of drug dose

Maintenance Dose

Go Maintenance Dose = Drug Clearance*Target Plasma Concentration/Bioavailability Of drug dose

Dose given volume of distribution and area under curve

Go Dose = Volume of Distribution*Elimination Rate Constant*Area Under Curve

Administrative Dose given Drug Purity

Go Administered Dose = Effective Dose/(Drug Purity*Bioavailability)

Effective dose given drug purity

Go Effective Dose = Drug Purity*Bioavailability*Administered Dose

Adult Dose of Drug by Clark's Equation in Micrograms

Go Adult Dose = Pediatric Dosage/(Weight of Patient in microgram/68)

Clark's Equation of Dosage in Microgram

Go Pediatric Dosage = Adult Dose*(Weight of Patient in microgram/68)

Dosing interval given average plasma concentration

Go Dosing Interval = Area Under Curve/Average Plasma Concentration

Adult Dose of Drug by Clark's Equation

Go Adult Dose = Pediatric Dosage/(Weight of Patient/150)

Weight of Patient by Clark's equation

Go Weight of Patient = (Pediatric Dosage/Adult Dose)*150

Clark's Equation of Dosage

Go Pediatric Dosage = Adult Dose*(Weight of Patient/150)

Weight of Patient in Kilograms by Clark's equation

Go Weight of Patient = (Pediatric Dosage/Adult Dose)*68

Amount of drug administered given apparent volume

Go Dose = Volume of Distribution*Concentration of Drug

Amount of drug in given volume of plasma

Go Concentration of Drug = Dose/Volume of Distribution

Administrative dose given effective dose and bioavailability

Go Administered Dose = Effective Dose/Bioavailability

Effective dose given bioavailability and administrative dose

Go Effective Dose = Bioavailability*Administered Dose

Amount of drug administered given area under curve

Go Dose = Volume of Plasma Cleared*Area Under Curve

Dosing interval given rate of administration Formula

Dosing Interval = (Administered Dose*Bioavailability*Drug Purity)/Drug Rate of Administration
Τ = (D_a*B*Q)/V_a

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Dosing interval given rate of administration?

Dosing interval given rate of administration calculator uses Dosing Interval = (Administered Dose*Bioavailability*Drug Purity)/Drug Rate of Administration to calculate the Dosing Interval, The Dosing interval given rate of administration formula is defined as direct relation with administered dose and inverse relation with the rate of administration of the drug. Dosing Interval is denoted by Τ symbol.

How to calculate Dosing interval given rate of administration using this online calculator? To use this online calculator for Dosing interval given rate of administration, enter Administered Dose (D_a), Bioavailability (B), Drug Purity (Q) & Drug Rate of Administration (V_a) and hit the calculate button. Here is how the Dosing interval given rate of administration calculation can be explained with given input values -> 0.067083 = (3.5E-09*12.5*69)/4.5E-05.

FAQ

What is Dosing interval given rate of administration?

The Dosing interval given rate of administration formula is defined as direct relation with administered dose and inverse relation with the rate of administration of the drug and is represented as Τ = (D_a*B*Q)/V_a or Dosing Interval = (Administered Dose*Bioavailability*Drug Purity)/Drug Rate of Administration. Administered Dose is the amount of drug administered for a pharmacological response, The Bioavailability is the systemically available fraction of a drug, The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present & Drug Rate of Administration is the amount of drug administered in a particular interval of time.

How to calculate Dosing interval given rate of administration?

The Dosing interval given rate of administration formula is defined as direct relation with administered dose and inverse relation with the rate of administration of the drug is calculated using Dosing Interval = (Administered Dose*Bioavailability*Drug Purity)/Drug Rate of Administration. To calculate Dosing interval given rate of administration, you need Administered Dose (D_a), Bioavailability (B), Drug Purity (Q) & Drug Rate of Administration (V_a). With our tool, you need to enter the respective value for Administered Dose, Bioavailability, Drug Purity & Drug Rate of Administration and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Dosing Interval?

In this formula, Dosing Interval uses Administered Dose, Bioavailability, Drug Purity & Drug Rate of Administration. We can use 1 other way(s) to calculate the same, which is/are as follows -

Dosing Interval = Area Under Curve/Average Plasma Concentration

Home

FREE PDFs

🔍 Search