Maximum Rate given Apparent Value of Michaelis Menten Constant Solution

STEP 0: Pre-Calculation Summary
Formula Used
Maximum Rate = (Initial Reaction Rate*(Apparent Michaelis Constant+Substrate Concentration))/Substrate Concentration
Vmax = (V0*(Kmapp+S))/S
This formula uses 4 Variables
Variables Used
Maximum Rate - (Measured in Mole per Cubic Meter Second) - The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.
Initial Reaction Rate - (Measured in Mole per Cubic Meter Second) - The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
Apparent Michaelis Constant - (Measured in Mole per Cubic Meter) - The Apparent Michaelis Constant is defined as the Michaelis–Menten constant in the presence of a competitive inhibitor.
Substrate Concentration - (Measured in Mole per Cubic Meter) - The Substrate Concentration is the number of moles of substrate per liter solution.
STEP 1: Convert Input(s) to Base Unit
Initial Reaction Rate: 0.45 Mole per Liter Second --> 450 Mole per Cubic Meter Second (Check conversion here)
Apparent Michaelis Constant: 12 Mole per Liter --> 12000 Mole per Cubic Meter (Check conversion here)
Substrate Concentration: 1.5 Mole per Liter --> 1500 Mole per Cubic Meter (Check conversion here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
Vmax = (V0*(Kmapp+S))/S --> (450*(12000+1500))/1500
Evaluating ... ...
Vmax = 4050
STEP 3: Convert Result to Output's Unit
4050 Mole per Cubic Meter Second -->4.05 Mole per Liter Second (Check conversion here)
FINAL ANSWER
4.05 Mole per Liter Second <-- Maximum Rate
(Calculation completed in 00.020 seconds)

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25 Michaelis Menten Kinetics Equation Calculators

Michaelis Constant given Modifying Factor in Michaelis Menten Equation
Go Michaelis Constant = (Substrate Concentration*((1/Enzyme Substrate Modifying Factor)*Maximum Rate)-Initial Reaction Rate)/((Enzyme Modifying Factor/Enzyme Substrate Modifying Factor)*Substrate Concentration)
Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation
Go Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration))
Modifying Factor of Enzyme Substrate Complex in Michaelis Menten Equation
Go Enzyme Substrate Modifying Factor = (((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Enzyme Modifying Factor*Michaelis Constant))/Substrate Concentration
Maximum Rate given Modifying Factor in Michaelis Menten Equation
Go Maximum Rate = (Initial Reaction Rate*((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration)))/Substrate Concentration
Modifying Factor of Enzyme in Michaelis Menten Equation
Go Enzyme Modifying Factor = (((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Enzyme Substrate Modifying Factor*Substrate Concentration))/Michaelis Constant
Catalytic Rate Constant from Michaelis Menten Kinetics Equation
Go Catalytic Rate Constant for MM = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/(Initial Enzyme Concentration*Substrate Concentration)
Enzyme Concentration from Michaelis Menten Kinetics equation
Go Initial Concentration of Enzyme = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/(Catalytic Rate Constant*Substrate Concentration)
Michaelis Constant given Catalytic Rate Constant and Initial Enzyme Concentration
Go Michaelis Constant = (Substrate Concentration*((Catalytic Rate Constant*Initial Enzyme Concentration)-Initial Reaction Rate))/Initial Reaction Rate
Michaelis Constant at Low Substrate Concentration
Go Michaelis Constant = (Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate
Dissociation Rate Constant from Michaelis Menten kinetics equation
Go Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Substrate Concentration)
Initial Rate given Apparent value of Michaelis Menten Constant
Go Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/(Apparent Michaelis Constant+Substrate Concentration)
Maximum Rate given Apparent Value of Michaelis Menten Constant
Go Maximum Rate = (Initial Reaction Rate*(Apparent Michaelis Constant+Substrate Concentration))/Substrate Concentration
Maximum Rate of System from Michaelis Menten Kinetics equation
Go Maximum Rate = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/Substrate Concentration
Substrate Concentration from Michaelis Menten Kinetics Equation
Go Substrate Concentration = (Michaelis Constant*Initial Reaction Rate)/(Maximum Rate-Initial Reaction Rate)
Michaelis Constant from Michaelis Menten kinetics equation
Go Michaelis Constant = Substrate Concentration*((Maximum Rate-Initial Reaction Rate)/Initial Reaction Rate)
Inhibitor's Dissociation Constant given Michaelis Menten Constant
Go Enzyme Inhibitor Dissociation Constant = (Inhibitor Concentration/((Apparent Michaelis Constant/Michaelis Constant)-1))
Michaelis Menten constant given Apparent Michaelis Menten Constant
Go Michaelis Constant = Apparent Michaelis Constant/(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))
Inhibitor Concentration given Apparent Michaelis Menten Constant
Go Inhibitor Concentration = ((Apparent Michaelis Constant/Michaelis Constant)-1)*Enzyme Inhibitor Dissociation Constant
Michaelis Constant given Forward, Reverse, and Catalytic Rate Constants
Go Michaelis Constant = (Reverse Rate Constant+Catalytic Rate Constant)/Forward Rate Constant
Catalytic rate constant given Michaelis Constant
Go Catalytic Rate Constant = (Michaelis Constant*Forward Rate Constant)-Reverse Rate Constant
Forward Rate Constant given Michaelis Constant
Go Forward Rate Constant = (Reverse Rate Constant+Catalytic Rate Constant)/Michaelis Constant
Michaelis Constant given Maximum Rate at Low Substrate Concentration
Go Michaelis Constant = (Maximum Rate*Substrate Concentration)/Initial Reaction Rate
Initial Enzyme Concentration if Substrate Concentration is Higher than Michaelis Constant
Go Enzyme Concentration Initially = Maximum Rate/Catalytic Rate Constant
Catalytic Rate Constant if Substrate Concentration is higher than Michaelis Constant
Go Catalytic Rate Constant = Maximum Rate/Initial Enzyme Concentration
Maximum Rate if Substrate Concentration is Higher than Michaelis Constant
Go Maximum Rate = Catalytic Rate Constant*Initial Enzyme Concentration

Maximum Rate given Apparent Value of Michaelis Menten Constant Formula

Maximum Rate = (Initial Reaction Rate*(Apparent Michaelis Constant+Substrate Concentration))/Substrate Concentration
Vmax = (V0*(Kmapp+S))/S

What is competitive Inhibition?

In competitive inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time, as shown in the figure on the right. This usually results from the inhibitor having an affinity for the active site of an enzyme where the substrate also binds; the substrate and inhibitor compete for access to the enzyme's active site. This type of inhibition can be overcome by sufficiently high concentrations of substrate (Vmax remains constant), i.e., by out-competing the inhibitor. However, the apparent Km will increase as it takes a higher concentration of the substrate to reach the Km point, or half the Vmax. Competitive inhibitors are often similar in structure to the real substrate.

How to Calculate Maximum Rate given Apparent Value of Michaelis Menten Constant?

Maximum Rate given Apparent Value of Michaelis Menten Constant calculator uses Maximum Rate = (Initial Reaction Rate*(Apparent Michaelis Constant+Substrate Concentration))/Substrate Concentration to calculate the Maximum Rate, The Maximum rate given apparent value of Michaelis Menten constant formula is defined as a plot of the reaction velocity (V0) associated with the concentration [S] of the substrate can then be used to determine values such as Vmax, initial velocity, and Km(app). Maximum Rate is denoted by Vmax symbol.

How to calculate Maximum Rate given Apparent Value of Michaelis Menten Constant using this online calculator? To use this online calculator for Maximum Rate given Apparent Value of Michaelis Menten Constant, enter Initial Reaction Rate (V0), Apparent Michaelis Constant (Kmapp) & Substrate Concentration (S) and hit the calculate button. Here is how the Maximum Rate given Apparent Value of Michaelis Menten Constant calculation can be explained with given input values -> 0.00405 = (450*(12000+1500))/1500.

FAQ

What is Maximum Rate given Apparent Value of Michaelis Menten Constant?
The Maximum rate given apparent value of Michaelis Menten constant formula is defined as a plot of the reaction velocity (V0) associated with the concentration [S] of the substrate can then be used to determine values such as Vmax, initial velocity, and Km(app) and is represented as Vmax = (V0*(Kmapp+S))/S or Maximum Rate = (Initial Reaction Rate*(Apparent Michaelis Constant+Substrate Concentration))/Substrate Concentration. The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place, The Apparent Michaelis Constant is defined as the Michaelis–Menten constant in the presence of a competitive inhibitor & The Substrate Concentration is the number of moles of substrate per liter solution.
How to calculate Maximum Rate given Apparent Value of Michaelis Menten Constant?
The Maximum rate given apparent value of Michaelis Menten constant formula is defined as a plot of the reaction velocity (V0) associated with the concentration [S] of the substrate can then be used to determine values such as Vmax, initial velocity, and Km(app) is calculated using Maximum Rate = (Initial Reaction Rate*(Apparent Michaelis Constant+Substrate Concentration))/Substrate Concentration. To calculate Maximum Rate given Apparent Value of Michaelis Menten Constant, you need Initial Reaction Rate (V0), Apparent Michaelis Constant (Kmapp) & Substrate Concentration (S). With our tool, you need to enter the respective value for Initial Reaction Rate, Apparent Michaelis Constant & Substrate Concentration and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Maximum Rate?
In this formula, Maximum Rate uses Initial Reaction Rate, Apparent Michaelis Constant & Substrate Concentration. We can use 3 other way(s) to calculate the same, which is/are as follows -
  • Maximum Rate = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/Substrate Concentration
  • Maximum Rate = Catalytic Rate Constant*Initial Enzyme Concentration
  • Maximum Rate = (Initial Reaction Rate*((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration)))/Substrate Concentration
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