Drug Rate Entering Body Solution

STEP 0: Pre-Calculation Summary
Formula Used
Absorption Rate Constant = ln(2)/Absorption Half Life
ka = ln(2)/ta/2
This formula uses 1 Functions, 2 Variables
Functions Used
ln - The natural logarithm, also known as the logarithm to the base e, is the inverse function of the natural exponential function., ln(Number)
Variables Used
Absorption Rate Constant - (Measured in 1 Per Second) - Absorption Rate Constant is the rate at which a drug enters into the body for oral and other extravascular routes.
Absorption Half Life - (Measured in Second) - The Absorption Half Life is the time for the concentration of the drug to double its original value for oral and other extravascular routes.
STEP 1: Convert Input(s) to Base Unit
Absorption Half Life: 0.69 Second --> 0.69 Second No Conversion Required
STEP 2: Evaluate Formula
Substituting Input Values in Formula
ka = ln(2)/ta/2 --> ln(2)/0.69
Evaluating ... ...
ka = 1.0045611312463
STEP 3: Convert Result to Output's Unit
1.0045611312463 1 Per Second -->3616.42007248667 1 Per Hour (Check conversion here)
FINAL ANSWER
3616.42007248667 3616.42 1 Per Hour <-- Absorption Rate Constant
(Calculation completed in 00.020 seconds)

Credits

Created by Prashant Singh
K J Somaiya College of science (K J Somaiya), Mumbai
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25 Drug Content Calculators

Saponification value
Go Saponification Value = Molecular weight of KOH*(Volume of blank-Volume of Actual solution)*Normality of solution/Weight of sample taken
Fraction of Drug Unbound in Tissue given Apparent Tissue Volume
Go Fraction Unbound in Tissue = (Fraction Unbound in Plasma*Apparent Tissue Volume)/(Volume of Distribution-Plasma Volume)
Secretion Rate of Drug
Go Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug)
Reabsorption Rate of Drug
Go Reabsorption Rate of Drug = ((Renal Clearance*Plasma Concentration)+Filtration Rate+Secretion Rate of Drug)
Filtration Rate of Drug
Go Filtration Rate = ((Renal Clearance*Plasma Concentration)+Reabsorption Rate of Drug-Secretion Rate of Drug)
Relative Bioavailability of Drug
Go Relative Bioavailability = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Dose Type A)
Acid Value of KOH
Go Acid Value = Molecular weight of KOH*Volume of solution koh*Normality of solution/Weight of sample taken
Drug Purity given Rate of Administration and Dosing Interval
Go Drug Purity = (Drug Rate*Dosing Interval)/(Administered Dose*Bioavailability)
Rate of Administration of Drug given Dosing Interval
Go Drug Rate = (Administered Dose*Bioavailability*Drug Purity)/Dosing Interval
Drug Purity given Administrative Dose and Effective Dose
Go Drug Purity = Effective Dose/(Administered Dose*Bioavailability)
Drug Loading Efficiency
Go Drug Loading Efficiency = Weight of drug in nanoparticles/Weight of the Nanoparticles*100
Encapsulation Efficiency
Go Encapsulation Efficiency = Weight of drug in nanoparticles/Weight of feeding drug*100
Renal Clearance of Drug
Go Renal Clearance = Drug Amount Excreted Unchanged in Urine/Area Under Curve
Concentration of Drug given Rate of Infusion of Drug
Go Concentration of Drug = Rate of Infusion/Volume of Plasma Cleared
Rate of Infusion of Drug
Go Rate of Infusion = Volume of Plasma Cleared*Concentration of Drug
Median Lethal Dose using Therapeutic Index
Go Median Lethal Dose = (Median Effective Dose*Therapeutic Index)
Margin of Safety of Drugs
Go Margin of Safety = Toxic Dose Response/Effective Dose Response
Effective Dose using Therapeutic Index
Go Median Effective Dose = Median Lethal Dose/Therapeutic Index
Therapeutic Index
Go Therapeutic Index = Median Lethal Dose/Median Effective Dose
Absorption Half-Life of Drug
Go Absorption Half Life = ln(2)/Absorption Rate Constant
Drug Rate Entering Body
Go Absorption Rate Constant = ln(2)/Absorption Half Life
Concentration of Drug using Volume of Distribution
Go Concentration of Drug = Dose/Volume of Distribution
Apparent Volume of Drug Distribution
Go Volume of Distribution = Dose/Concentration of Drug
Tablet Dosage
Go Number of tablet = Desired dosage/Stock strength
Easter Value
Go Easter Value = Saponification Value-Acid Value

Drug Rate Entering Body Formula

Absorption Rate Constant = ln(2)/Absorption Half Life
ka = ln(2)/ta/2

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Drug Rate Entering Body?

Drug Rate Entering Body calculator uses Absorption Rate Constant = ln(2)/Absorption Half Life to calculate the Absorption Rate Constant, The Drug Rate Entering Body formula is defined as the inverse relation of time with the rate constant. Absorption Rate Constant is denoted by ka symbol.

How to calculate Drug Rate Entering Body using this online calculator? To use this online calculator for Drug Rate Entering Body, enter Absorption Half Life (ta/2) and hit the calculate button. Here is how the Drug Rate Entering Body calculation can be explained with given input values -> 1.3E+7 = ln(2)/0.69.

FAQ

What is Drug Rate Entering Body?
The Drug Rate Entering Body formula is defined as the inverse relation of time with the rate constant and is represented as ka = ln(2)/ta/2 or Absorption Rate Constant = ln(2)/Absorption Half Life. The Absorption Half Life is the time for the concentration of the drug to double its original value for oral and other extravascular routes.
How to calculate Drug Rate Entering Body?
The Drug Rate Entering Body formula is defined as the inverse relation of time with the rate constant is calculated using Absorption Rate Constant = ln(2)/Absorption Half Life. To calculate Drug Rate Entering Body, you need Absorption Half Life (ta/2). With our tool, you need to enter the respective value for Absorption Half Life and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
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