Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration Solution

STEP 0: Pre-Calculation Summary
Formula Used
Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration
k2 = V0/ES
This formula uses 3 Variables
Variables Used
Final Rate Constant - (Measured in 1 Per Second) - The Final Rate Constant is the rate constant when the enzyme-substrate complex on reaction with inhibitor is converted into the enzyme catalyst and product.
Initial Reaction Rate - (Measured in Mole per Cubic Meter Second) - The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
Enzyme Substrate Complex Concentration - (Measured in Mole per Cubic Meter) - The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate.
STEP 1: Convert Input(s) to Base Unit
Initial Reaction Rate: 0.45 Mole per Liter Second --> 450 Mole per Cubic Meter Second (Check conversion here)
Enzyme Substrate Complex Concentration: 10 Mole per Liter --> 10000 Mole per Cubic Meter (Check conversion here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
k2 = V0/ES --> 450/10000
Evaluating ... ...
k2 = 0.045
STEP 3: Convert Result to Output's Unit
0.045 1 Per Second --> No Conversion Required
FINAL ANSWER
0.045 1 Per Second <-- Final Rate Constant
(Calculation completed in 00.004 seconds)

Credits

Created by Prashant Singh
K J Somaiya College of science (K J Somaiya), Mumbai
Prashant Singh has created this Calculator and 700+ more calculators!
Verified by Prerana Bakli
University of Hawaiʻi at Mānoa (UH Manoa), Hawaii, USA
Prerana Bakli has verified this Calculator and 1600+ more calculators!

16 Rate Constants of Enzymatic Reaction Calculators

Forward Rate Constant in Enzymatic Reaction mechanism
Go Forward Rate Constant = (Reverse Rate Constant*Enzyme Substrate Complex Concentration)/(Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))
Reverse Rate Constant in Enzymatic Reaction Mechanism
Go Reverse Rate Constant = (Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex Concentration
Forward Rate Constant given Reverse and Catalytic Rate Constant
Go Forward Rate Constant = (Reverse Rate Constant+Catalytic Rate Constant)*(Enzyme Substrate Complex Concentration/(Catalyst Concentration*Substrate Concentration))
Reverse Rate Constant given Forward and Catalytic Rate Constants
Go Reverse Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Catalytic Rate Constant
Catalytic Rate Constant given Reverse and Forward Rate Constant
Go Catalytic Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Reverse Rate Constant
Catalytic Rate Constant given Dissociation Rate Constant
Go Catalytic Rate Constant = (Initial Reaction Rate*(Dissociation Rate Constant+Substrate Concentration))/(Initial Enzyme Concentration*Substrate Concentration)
Dissociation Rate Constant given Catalytic Rate Constant
Go Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration
Catalytic Rate Constant at Low Substrate Concentration
Go Catalytic Rate Constant = (Initial Reaction Rate*Michaelis Constant)/(Initial Enzyme Concentration*Substrate Concentration)
Dissociation Rate Constant given Concentration of Enzyme and Substrate
Go Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration
Reverse Rate Constant given Michaelis Constant
Go Reverse Rate Constant = (Michaelis Constant*Forward Rate Constant)-Catalytic Rate Constant
Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration
Go Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration
Forward Rate Constant given Dissociation Rate Constant
Go Forward Rate Constant = (Reverse Rate Constant/Dissociation Rate Constant)
Reverse Rate Constant given Dissociation Rate Constant
Go Reverse Rate Constant = (Dissociation Rate Constant*Forward Rate Constant)
Dissociation Rate Constant in Enzymatic Reaction Mechanism
Go Dissociation Rate Constant = Reverse Rate Constant/Forward Rate Constant
Rate of Chemical Reaction
Go Rate of chemical reaction = Change in concentration/Total time interval
Rate Constant given Maximum Rate and Initial Enzyme Concentration
Go Final Rate Constant = Maximum Rate/Initial Enzyme Concentration

Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration Formula

Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration
k2 = V0/ES

What is competitive Inhibition?

In competitive inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time, as shown in the figure on the right. This usually results from the inhibitor having an affinity for the active site of an enzyme where the substrate also binds; the substrate and inhibitor compete for access to the enzyme's active site. This type of inhibition can be overcome by sufficiently high concentrations of substrate (Vmax remains constant), i.e., by out-competing the inhibitor. However, the apparent Km will increase as it takes a higher concentration of the substrate to reach the Km point, or half the Vmax. Competitive inhibitors are often similar in structure to the real substrate.

How to Calculate Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration?

Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration calculator uses Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration to calculate the Final Rate Constant, The Rate constant given initial rate and enzyme substrate complex concentration formula is defined as the ratio of the initial rate of the system to the concentration of enzyme-substrate complex. Final Rate Constant is denoted by k2 symbol.

How to calculate Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration using this online calculator? To use this online calculator for Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration, enter Initial Reaction Rate (V0) & Enzyme Substrate Complex Concentration (ES) and hit the calculate button. Here is how the Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration calculation can be explained with given input values -> 0.045 = 450/10000.

FAQ

What is Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration?
The Rate constant given initial rate and enzyme substrate complex concentration formula is defined as the ratio of the initial rate of the system to the concentration of enzyme-substrate complex and is represented as k2 = V0/ES or Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration. The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place & The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate.
How to calculate Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration?
The Rate constant given initial rate and enzyme substrate complex concentration formula is defined as the ratio of the initial rate of the system to the concentration of enzyme-substrate complex is calculated using Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration. To calculate Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration, you need Initial Reaction Rate (V0) & Enzyme Substrate Complex Concentration (ES). With our tool, you need to enter the respective value for Initial Reaction Rate & Enzyme Substrate Complex Concentration and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Final Rate Constant?
In this formula, Final Rate Constant uses Initial Reaction Rate & Enzyme Substrate Complex Concentration. We can use 1 other way(s) to calculate the same, which is/are as follows -
  • Final Rate Constant = Maximum Rate/Initial Enzyme Concentration
Let Others Know
Facebook
Twitter
Reddit
LinkedIn
Email
WhatsApp
Copied!