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K J Somaiya College of science (K J Somaiya), Mumbai
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National Institute of Technology, Meghalaya (NIT), Meghalaya
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Bioavailability given drug purity Solution

STEP 0: Pre-Calculation Summary
Formula Used
bioavailability = Effective dose/(Drug purity*Administered dose)
B = De/(Q*Da)
This formula uses 3 Variables
Variables Used
Effective dose - The Effective dose is a dose or concentration of a drug that produces a biological response. (Measured in Microgram)
Drug purity- The Drug purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.
Administered dose - The Administered dose is the amount of drug administered for a pharmacological response. (Measured in Microgram)
STEP 1: Convert Input(s) to Base Unit
Effective dose: 80 Microgram --> 8E-08 Kilogram (Check conversion here)
Drug purity: 69 --> No Conversion Required
Administered dose: 100 Microgram --> 1E-07 Kilogram (Check conversion here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
B = De/(Q*Da) --> 8E-08/(69*1E-07)
Evaluating ... ...
B = 0.0115942028985507
STEP 3: Convert Result to Output's Unit
0.0115942028985507 --> No Conversion Required
FINAL ANSWER
0.0115942028985507 <-- Bioavailability
(Calculation completed in 00.000 seconds)

4 Bioavailability Calculators

Bioavailability of drug
bioavailability_of_drug = (Area under curve nonintravenous*Dose intravenous)/(Area under curve intravenous*Dose nonintravenous) Go
Bioavailability given rate of administration and dosing interval
bioavailability = (Drug rate of administration*Dosing interval)/(Administered dose*Drug purity) Go
Bioavailability given drug purity
bioavailability = Effective dose/(Drug purity*Administered dose) Go
Bioavailability given effective and administrative dose
bioavailability = Effective dose/Administered dose Go

Bioavailability given drug purity Formula

bioavailability = Effective dose/(Drug purity*Administered dose)
B = De/(Q*Da)

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Bioavailability given drug purity?

Bioavailability given drug purity calculator uses bioavailability = Effective dose/(Drug purity*Administered dose) to calculate the Bioavailability, The Bioavailability given drug purity formula is defined as the ratio of the effective dose to the drug purity of the administered dose. Bioavailability is denoted by B symbol.

How to calculate Bioavailability given drug purity using this online calculator? To use this online calculator for Bioavailability given drug purity, enter Effective dose (De), Drug purity (Q) & Administered dose (Da) and hit the calculate button. Here is how the Bioavailability given drug purity calculation can be explained with given input values -> 0.011594 = 8E-08/(69*1E-07).

FAQ

What is Bioavailability given drug purity?
The Bioavailability given drug purity formula is defined as the ratio of the effective dose to the drug purity of the administered dose and is represented as B = De/(Q*Da) or bioavailability = Effective dose/(Drug purity*Administered dose). The Effective dose is a dose or concentration of a drug that produces a biological response, The Drug purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present & The Administered dose is the amount of drug administered for a pharmacological response.
How to calculate Bioavailability given drug purity?
The Bioavailability given drug purity formula is defined as the ratio of the effective dose to the drug purity of the administered dose is calculated using bioavailability = Effective dose/(Drug purity*Administered dose). To calculate Bioavailability given drug purity, you need Effective dose (De), Drug purity (Q) & Administered dose (Da). With our tool, you need to enter the respective value for Effective dose, Drug purity & Administered dose and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Bioavailability?
In this formula, Bioavailability uses Effective dose, Drug purity & Administered dose. We can use 4 other way(s) to calculate the same, which is/are as follows -
  • bioavailability_of_drug = (Area under curve nonintravenous*Dose intravenous)/(Area under curve intravenous*Dose nonintravenous)
  • bioavailability = Effective dose/Administered dose
  • bioavailability = Effective dose/(Drug purity*Administered dose)
  • bioavailability = (Drug rate of administration*Dosing interval)/(Administered dose*Drug purity)
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