Enzyme Substrate Complex Concentration given Rate Constant and Initial Rate Solution

STEP 0: Pre-Calculation Summary
Formula Used
Enzyme Inhibitor Complex Concentration = (Initial Reaction Rate/Final Rate Constant)
EI = (V0/k2)
This formula uses 3 Variables
Variables Used
Enzyme Inhibitor Complex Concentration - (Measured in Mole per Cubic Meter) - The Enzyme Inhibitor Complex Concentration is the number of moles of enzyme inhibitor substrate complex per liter of the enzymatic solution.
Initial Reaction Rate - (Measured in Mole per Cubic Meter Second) - The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
Final Rate Constant - (Measured in 1 Per Second) - The Final Rate Constant is the rate constant when the enzyme-substrate complex on reaction with inhibitor is converted into the enzyme catalyst and product.
STEP 1: Convert Input(s) to Base Unit
Initial Reaction Rate: 0.45 Mole per Liter Second --> 450 Mole per Cubic Meter Second (Check conversion here)
Final Rate Constant: 23 1 Per Second --> 23 1 Per Second No Conversion Required
STEP 2: Evaluate Formula
Substituting Input Values in Formula
EI = (V0/k2) --> (450/23)
Evaluating ... ...
EI = 19.5652173913043
STEP 3: Convert Result to Output's Unit
19.5652173913043 Mole per Cubic Meter -->0.0195652173913043 Mole per Liter (Check conversion here)
FINAL ANSWER
0.0195652173913043 0.019565 Mole per Liter <-- Enzyme Inhibitor Complex Concentration
(Calculation completed in 00.020 seconds)

Credits

Created by Prashant Singh
K J Somaiya College of science (K J Somaiya), Mumbai
Prashant Singh has created this Calculator and 700+ more calculators!
Verified by Prerana Bakli
University of Hawaiʻi at Mānoa (UH Manoa), Hawaii, USA
Prerana Bakli has verified this Calculator and 1600+ more calculators!

21 Complex Concentration Calculators

Enzyme Substrate Complex Concentration in Instantaneous Chemical Equilibrium
Go Enzyme Substrate Complex Concentration = (Forward Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/(Reverse Rate Constant+(Forward Rate Constant*Substrate Concentration))
Initial Enzyme Concentration in Enzymatic Reaction Mechanism
Go Initial Enzyme Concentration = ((Reverse Rate Constant*Enzyme Substrate Complex Concentration)/(Forward Rate Constant*Substrate Concentration))+Enzyme Substrate Complex Concentration
Substrate Concentration in Enzymatic Reaction Mechanism
Go Substrate Concentration = (Reverse Rate Constant*Enzyme Substrate Complex Concentration)/(Forward Rate Constant*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))
Enzyme Catalyst Concentration given Forward, Reverse, and Catalytic Rate Constants
Go Catalyst Concentration = ((Reverse Rate Constant+Catalytic Rate Constant)*Enzyme Substrate Complex Concentration)/(Forward Rate Constant*Substrate Concentration)
Substrate Concentration given Forward, Reverse, and Catalytic Rate Constants
Go Substrate Concentration = ((Reverse Rate Constant+Catalytic Rate Constant)*Enzyme Substrate Complex Concentration)/(Forward Rate Constant*Catalyst Concentration)
Initial Enzyme Concentration given Catalytic Rate Constant and Dissociation Rate Constants
Go Initial Enzyme Concentration = (Initial Reaction Rate*(Dissociation Rate Constant+Substrate Concentration))/(Catalytic Rate Constant*Substrate Concentration)
Substrate Concentration given Catalytic Rate Constant and Dissociation Rate Constants
Go Substrate Concentration = (Dissociation Rate Constant*Initial Reaction Rate)/((Catalytic Rate Constant*Initial Enzyme Concentration)-Initial Reaction Rate)
Substrate Concentration given Catalytic Rate Constant and Initial Enzyme Concentration
Go Concentration of Substrate = (Michaelis Constant*Initial Reaction Rate)/((Catalytic Rate Constant*Initial Enzyme Concentration)-Initial Reaction Rate)
Substrate Concentration given Dissociation Rate Constant
Go Substrate Concentration = (Dissociation Rate Constant*Enzyme Substrate Complex Concentration)/(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration)
Initial Enzyme Concentration given Dissociation Rate Constant
Go Enzyme Concentration Initially = (Enzyme Substrate Complex Concentration*(Dissociation Rate Constant+Substrate Concentration))/(Substrate Concentration)
Enzyme Substrate Complex Concentration given Dissociation Rate Constant
Go Enzyme Substrate Complex Concentration = (Initial Enzyme Concentration*Substrate Concentration)/(Dissociation Rate Constant+Substrate Concentration)
Substrate Concentration if Michaelis Constant is very Large than Substrate Concentration
Go Substrate Concentration = (Initial Reaction Rate*Michaelis Constant)/(Catalytic Rate Constant*Initial Enzyme Concentration)
Initial Enzyme Concentration at Low Substrate Concentration
Go Initial Enzyme Concentration = (Initial Reaction Rate*Michaelis Constant)/(Catalytic Rate Constant*Substrate Concentration)
Inhibitor Concentration given Apparent Initial Enzyme Concentration
Go Inhibitor Concentration for CI = ((Initial Enzyme Concentration/Apparent Initial Enzyme Concentration)-1)*Enzyme Inhibitor Dissociation Constant
Substrate Concentration given Maximum Rate and Dissociation Rate Constant
Go Substrate Concentration = (Dissociation Rate Constant*Initial Reaction Rate)/(Maximum Rate-Initial Reaction Rate)
Substrate Concentration given Maximum Rate at Low Concentration
Go Substrate Concentration = (Initial Reaction Rate*Michaelis Constant)/Maximum Rate
Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex
Go Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant
Inhibitor Concentration given Enzyme Substrate Modifying Factor
Go Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant
Inhibitor Concentration given Modifying Factor of Enzyme
Go Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant
Enzyme Substrate Complex Concentration given Rate Constant and Initial Rate
Go Enzyme Inhibitor Complex Concentration = (Initial Reaction Rate/Final Rate Constant)
Initial Enzyme Concentration given Rate Constant and Maximum Rate
Go Initial Enzyme Concentration = Maximum Rate/Final Rate Constant

Enzyme Substrate Complex Concentration given Rate Constant and Initial Rate Formula

Enzyme Inhibitor Complex Concentration = (Initial Reaction Rate/Final Rate Constant)
EI = (V0/k2)

What is competitive Inhibition?

In competitive inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time, as shown in the figure on the right. This usually results from the inhibitor having an affinity for the active site of an enzyme where the substrate also binds; the substrate and inhibitor compete for access to the enzyme's active site. This type of inhibition can be overcome by sufficiently high concentrations of substrate (Vmax remains constant), i.e., by out-competing the inhibitor. However, the apparent Km will increase as it takes a higher concentration of the substrate to reach the Km point, or half the Vmax. Competitive inhibitors are often similar in structure to the real substrate.

How to Calculate Enzyme Substrate Complex Concentration given Rate Constant and Initial Rate?

Enzyme Substrate Complex Concentration given Rate Constant and Initial Rate calculator uses Enzyme Inhibitor Complex Concentration = (Initial Reaction Rate/Final Rate Constant) to calculate the Enzyme Inhibitor Complex Concentration, The Enzyme substrate complex concentration given rate constant and initial rate formula is defined as the ratio of the initial rate of the system to the rate constant of the reaction converting enzyme-substrate intermediate to the product. Enzyme Inhibitor Complex Concentration is denoted by EI symbol.

How to calculate Enzyme Substrate Complex Concentration given Rate Constant and Initial Rate using this online calculator? To use this online calculator for Enzyme Substrate Complex Concentration given Rate Constant and Initial Rate, enter Initial Reaction Rate (V0) & Final Rate Constant (k2) and hit the calculate button. Here is how the Enzyme Substrate Complex Concentration given Rate Constant and Initial Rate calculation can be explained with given input values -> 2E-5 = (450/23).

FAQ

What is Enzyme Substrate Complex Concentration given Rate Constant and Initial Rate?
The Enzyme substrate complex concentration given rate constant and initial rate formula is defined as the ratio of the initial rate of the system to the rate constant of the reaction converting enzyme-substrate intermediate to the product and is represented as EI = (V0/k2) or Enzyme Inhibitor Complex Concentration = (Initial Reaction Rate/Final Rate Constant). The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place & The Final Rate Constant is the rate constant when the enzyme-substrate complex on reaction with inhibitor is converted into the enzyme catalyst and product.
How to calculate Enzyme Substrate Complex Concentration given Rate Constant and Initial Rate?
The Enzyme substrate complex concentration given rate constant and initial rate formula is defined as the ratio of the initial rate of the system to the rate constant of the reaction converting enzyme-substrate intermediate to the product is calculated using Enzyme Inhibitor Complex Concentration = (Initial Reaction Rate/Final Rate Constant). To calculate Enzyme Substrate Complex Concentration given Rate Constant and Initial Rate, you need Initial Reaction Rate (V0) & Final Rate Constant (k2). With our tool, you need to enter the respective value for Initial Reaction Rate & Final Rate Constant and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
Let Others Know
Facebook
Twitter
Reddit
LinkedIn
Email
WhatsApp
Copied!