Maximum Rate given Modifying Factor in Michaelis Menten Equation Calculator

✖The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.ⓘ Initial Reaction Rate [V₀]			+10% -10%
✖The Enzyme Modifying Factor is defined by the inhibitor concentration and the dissociation constants of enzyme.ⓘ Enzyme Modifying Factor [α]			+10% -10%
✖The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system.ⓘ Michaelis Constant [K_M]			+10% -10%
✖The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.ⓘ Enzyme Substrate Modifying Factor [α^']			+10% -10%
✖The Substrate Concentration is the number of moles of substrate per liter solution.ⓘ Substrate Concentration [S]			+10% -10%

✖The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.ⓘ Maximum Rate given Modifying Factor in Michaelis Menten Equation [V_max]

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Maximum Rate given Modifying Factor in Michaelis Menten Equation

Formula

`"V"_{"max"} = ("V"_{"0"}*(("α"*"K"_{"M"})+("α"^{"'"}*"S")))/"S"`

Example

`"5.4mol/L*s"=("0.45mol/L*s"*(("5"*"3mol/L")+("2"*"1.5mol/L")))/"1.5mol/L"`

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Maximum Rate given Modifying Factor in Michaelis Menten Equation Solution

STEP 0: Pre-Calculation Summary

Formula Used

Maximum Rate = (Initial Reaction Rate*((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration)))/Substrate Concentration
V_max = (V₀*((α*K_M)+(α^'*S)))/S
This formula uses 6 Variables

Variables Used

Maximum Rate - (Measured in Mole per Cubic Meter Second) - The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.
Initial Reaction Rate - (Measured in Mole per Cubic Meter Second) - The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
Enzyme Modifying Factor - The Enzyme Modifying Factor is defined by the inhibitor concentration and the dissociation constants of enzyme.
Michaelis Constant - (Measured in Mole per Cubic Meter) - The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system.
Enzyme Substrate Modifying Factor - The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.
Substrate Concentration - (Measured in Mole per Cubic Meter) - The Substrate Concentration is the number of moles of substrate per liter solution.

STEP 1: Convert Input(s) to Base Unit

Initial Reaction Rate: 0.45 Mole per Liter Second --> 450 Mole per Cubic Meter Second (Check conversion here)
Enzyme Modifying Factor: 5 --> No Conversion Required
Michaelis Constant: 3 Mole per Liter --> 3000 Mole per Cubic Meter (Check conversion here)
Enzyme Substrate Modifying Factor: 2 --> No Conversion Required
Substrate Concentration: 1.5 Mole per Liter --> 1500 Mole per Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

V_max = (V₀*((α*K_M)+(α^'*S)))/S --> (450*((5*3000)+(2*1500)))/1500

Evaluating ... ...

V_max = 5400

STEP 3: Convert Result to Output's Unit

5400 Mole per Cubic Meter Second -->5.4 Mole per Liter Second (Check conversion here)

FINAL ANSWER

5.4 Mole per Liter Second <-- Maximum Rate

(Calculation completed in 00.004 seconds)

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< 25 Michaelis Menten Kinetics Equation Calculators

Michaelis Constant given Modifying Factor in Michaelis Menten Equation

Go Michaelis Constant = (Substrate Concentration*((1/Enzyme Substrate Modifying Factor)*Maximum Rate)-Initial Reaction Rate)/((Enzyme Modifying Factor/Enzyme Substrate Modifying Factor)*Substrate Concentration)

Initial Reaction Rate of Enzyme given Modifying factor in Michaelis Menten equation

Go Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration))

Modifying Factor of Enzyme Substrate Complex in Michaelis Menten Equation

Go Enzyme Substrate Modifying Factor = (((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Enzyme Modifying Factor*Michaelis Constant))/Substrate Concentration

Maximum Rate given Modifying Factor in Michaelis Menten Equation

Go Maximum Rate = (Initial Reaction Rate*((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration)))/Substrate Concentration

Modifying Factor of Enzyme in Michaelis Menten Equation

Go Enzyme Modifying Factor = (((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Enzyme Substrate Modifying Factor*Substrate Concentration))/Michaelis Constant

Catalytic Rate Constant from Michaelis Menten Kinetics Equation

Go Catalytic Rate Constant for MM = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/(Initial Enzyme Concentration*Substrate Concentration)

Enzyme Concentration from Michaelis Menten Kinetics equation

Go Initial Concentration of Enzyme = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/(Catalytic Rate Constant*Substrate Concentration)

Michaelis Constant given Catalytic Rate Constant and Initial Enzyme Concentration

Go Michaelis Constant = (Substrate Concentration*((Catalytic Rate Constant*Initial Enzyme Concentration)-Initial Reaction Rate))/Initial Reaction Rate

Michaelis Constant at Low Substrate Concentration

Go Michaelis Constant = (Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate

Dissociation Rate Constant from Michaelis Menten kinetics equation

Go Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-(Substrate Concentration)

Initial Rate given Apparent value of Michaelis Menten Constant

Go Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/(Apparent Michaelis Constant+Substrate Concentration)

Maximum Rate given Apparent Value of Michaelis Menten Constant

Go Maximum Rate = (Initial Reaction Rate*(Apparent Michaelis Constant+Substrate Concentration))/Substrate Concentration

Maximum Rate of System from Michaelis Menten Kinetics equation

Go Maximum Rate = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/Substrate Concentration

Substrate Concentration from Michaelis Menten Kinetics Equation

Go Substrate Concentration = (Michaelis Constant*Initial Reaction Rate)/(Maximum Rate-Initial Reaction Rate)

Michaelis Constant from Michaelis Menten kinetics equation

Go Michaelis Constant = Substrate Concentration*((Maximum Rate-Initial Reaction Rate)/Initial Reaction Rate)

Inhibitor's Dissociation Constant given Michaelis Menten Constant

Go Enzyme Inhibitor Dissociation Constant = (Inhibitor Concentration/((Apparent Michaelis Constant/Michaelis Constant)-1))

Michaelis Menten constant given Apparent Michaelis Menten Constant

Go Michaelis Constant = Apparent Michaelis Constant/(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))

Inhibitor Concentration given Apparent Michaelis Menten Constant

Go Inhibitor Concentration = ((Apparent Michaelis Constant/Michaelis Constant)-1)*Enzyme Inhibitor Dissociation Constant

Michaelis Constant given Forward, Reverse, and Catalytic Rate Constants

Go Michaelis Constant = (Reverse Rate Constant+Catalytic Rate Constant)/Forward Rate Constant

Catalytic rate constant given Michaelis Constant

Go Catalytic Rate Constant = (Michaelis Constant*Forward Rate Constant)-Reverse Rate Constant

Forward Rate Constant given Michaelis Constant

Go Forward Rate Constant = (Reverse Rate Constant+Catalytic Rate Constant)/Michaelis Constant

Michaelis Constant given Maximum Rate at Low Substrate Concentration

Go Michaelis Constant = (Maximum Rate*Substrate Concentration)/Initial Reaction Rate

Initial Enzyme Concentration if Substrate Concentration is Higher than Michaelis Constant

Go Enzyme Concentration Initially = Maximum Rate/Catalytic Rate Constant

Catalytic Rate Constant if Substrate Concentration is higher than Michaelis Constant

Go Catalytic Rate Constant = Maximum Rate/Initial Enzyme Concentration

Maximum Rate if Substrate Concentration is Higher than Michaelis Constant

Go Maximum Rate = Catalytic Rate Constant*Initial Enzyme Concentration

Maximum Rate given Modifying Factor in Michaelis Menten Equation Formula

What is competitive Inhibition?

In competitive inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time, as shown in the figure on the right. This usually results from the inhibitor having an affinity for the active site of an enzyme where the substrate also binds; the substrate and inhibitor compete for access to the enzyme's active site. This type of inhibition can be overcome by sufficiently high concentrations of substrate (Vmax remains constant), i.e., by out-competing the inhibitor. However, the apparent Km will increase as it takes a higher concentration of the substrate to reach the Km point, or half the Vmax. Competitive inhibitors are often similar in structure to the real substrate.

How to Calculate Maximum Rate given Modifying Factor in Michaelis Menten Equation?

Maximum Rate given Modifying Factor in Michaelis Menten Equation calculator uses Maximum Rate = (Initial Reaction Rate*((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration)))/Substrate Concentration to calculate the Maximum Rate, The Maximum rate given modifying factor in Michaelis Menten equation formula is defined as the enzyme activity under various substrate and inhibitor concentrations, to obtain a modified Michaelis–Menten equation. Maximum Rate is denoted by V_max symbol.

How to calculate Maximum Rate given Modifying Factor in Michaelis Menten Equation using this online calculator? To use this online calculator for Maximum Rate given Modifying Factor in Michaelis Menten Equation, enter Initial Reaction Rate (V₀), Enzyme Modifying Factor (α), Michaelis Constant (K_M), Enzyme Substrate Modifying Factor (α^') & Substrate Concentration (S) and hit the calculate button. Here is how the Maximum Rate given Modifying Factor in Michaelis Menten Equation calculation can be explained with given input values -> 0.0054 = (450*((5*3000)+(2*1500)))/1500.

FAQ

What is Maximum Rate given Modifying Factor in Michaelis Menten Equation?

The Maximum rate given modifying factor in Michaelis Menten equation formula is defined as the enzyme activity under various substrate and inhibitor concentrations, to obtain a modified Michaelis–Menten equation and is represented as V_max = (V₀*((α*K_M)+(α^'*S)))/S or Maximum Rate = (Initial Reaction Rate*((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration)))/Substrate Concentration. The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place, The Enzyme Modifying Factor is defined by the inhibitor concentration and the dissociation constants of enzyme, The Michaelis Constant is numerically equal to the substrate concentration at which the reaction rate is half of the maximum rate of the system, The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex & The Substrate Concentration is the number of moles of substrate per liter solution.

How to calculate Maximum Rate given Modifying Factor in Michaelis Menten Equation?

The Maximum rate given modifying factor in Michaelis Menten equation formula is defined as the enzyme activity under various substrate and inhibitor concentrations, to obtain a modified Michaelis–Menten equation is calculated using Maximum Rate = (Initial Reaction Rate*((Enzyme Modifying Factor*Michaelis Constant)+(Enzyme Substrate Modifying Factor*Substrate Concentration)))/Substrate Concentration. To calculate Maximum Rate given Modifying Factor in Michaelis Menten Equation, you need Initial Reaction Rate (V₀), Enzyme Modifying Factor (α), Michaelis Constant (K_M), Enzyme Substrate Modifying Factor (α^') & Substrate Concentration (S). With our tool, you need to enter the respective value for Initial Reaction Rate, Enzyme Modifying Factor, Michaelis Constant, Enzyme Substrate Modifying Factor & Substrate Concentration and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Maximum Rate?

In this formula, Maximum Rate uses Initial Reaction Rate, Enzyme Modifying Factor, Michaelis Constant, Enzyme Substrate Modifying Factor & Substrate Concentration. We can use 3 other way(s) to calculate the same, which is/are as follows -

Maximum Rate = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/Substrate Concentration
Maximum Rate = Catalytic Rate Constant*Initial Enzyme Concentration
Maximum Rate = (Initial Reaction Rate*(Apparent Michaelis Constant+Substrate Concentration))/Substrate Concentration

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