Reverse Rate Constant in Enzymatic Reaction Mechanism Solution

STEP 0: Pre-Calculation Summary
Formula Used
Reverse Rate Constant = (Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex Concentration
kr = (kf*S*([E0]-ES))/ES
This formula uses 5 Variables
Variables Used
Reverse Rate Constant - (Measured in Mole per Cubic Meter Second) - The Reverse Rate Constant is defined as the rate constant for the backward reaction.
Forward Rate Constant - (Measured in 1 Per Second) - The Forward Rate Constant is defined as the rate constant for the forward occurring reaction.
Substrate Concentration - (Measured in Mole per Cubic Meter) - The Substrate Concentration is the number of moles of substrate per liter solution.
Initial Enzyme Concentration - (Measured in Mole per Cubic Meter) - The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction.
Enzyme Substrate Complex Concentration - (Measured in Mole per Cubic Meter) - The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate.
STEP 1: Convert Input(s) to Base Unit
Forward Rate Constant: 6.9 1 Per Second --> 6.9 1 Per Second No Conversion Required
Substrate Concentration: 1.5 Mole per Liter --> 1500 Mole per Cubic Meter (Check conversion here)
Initial Enzyme Concentration: 100 Mole per Liter --> 100000 Mole per Cubic Meter (Check conversion here)
Enzyme Substrate Complex Concentration: 10 Mole per Liter --> 10000 Mole per Cubic Meter (Check conversion here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
kr = (kf*S*([E0]-ES))/ES --> (6.9*1500*(100000-10000))/10000
Evaluating ... ...
kr = 93150
STEP 3: Convert Result to Output's Unit
93150 Mole per Cubic Meter Second -->93.15 Mole per Liter Second (Check conversion here)
FINAL ANSWER
93.15 Mole per Liter Second <-- Reverse Rate Constant
(Calculation completed in 00.004 seconds)

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16 Rate Constants of Enzymatic Reaction Calculators

Forward Rate Constant in Enzymatic Reaction mechanism
Go Forward Rate Constant = (Reverse Rate Constant*Enzyme Substrate Complex Concentration)/(Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))
Reverse Rate Constant in Enzymatic Reaction Mechanism
Go Reverse Rate Constant = (Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex Concentration
Forward Rate Constant given Reverse and Catalytic Rate Constant
Go Forward Rate Constant = (Reverse Rate Constant+Catalytic Rate Constant)*(Enzyme Substrate Complex Concentration/(Catalyst Concentration*Substrate Concentration))
Reverse Rate Constant given Forward and Catalytic Rate Constants
Go Reverse Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Catalytic Rate Constant
Catalytic Rate Constant given Reverse and Forward Rate Constant
Go Catalytic Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Reverse Rate Constant
Catalytic Rate Constant given Dissociation Rate Constant
Go Catalytic Rate Constant = (Initial Reaction Rate*(Dissociation Rate Constant+Substrate Concentration))/(Initial Enzyme Concentration*Substrate Concentration)
Dissociation Rate Constant given Catalytic Rate Constant
Go Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration
Catalytic Rate Constant at Low Substrate Concentration
Go Catalytic Rate Constant = (Initial Reaction Rate*Michaelis Constant)/(Initial Enzyme Concentration*Substrate Concentration)
Dissociation Rate Constant given Concentration of Enzyme and Substrate
Go Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration
Reverse Rate Constant given Michaelis Constant
Go Reverse Rate Constant = (Michaelis Constant*Forward Rate Constant)-Catalytic Rate Constant
Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration
Go Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration
Forward Rate Constant given Dissociation Rate Constant
Go Forward Rate Constant = (Reverse Rate Constant/Dissociation Rate Constant)
Reverse Rate Constant given Dissociation Rate Constant
Go Reverse Rate Constant = (Dissociation Rate Constant*Forward Rate Constant)
Dissociation Rate Constant in Enzymatic Reaction Mechanism
Go Dissociation Rate Constant = Reverse Rate Constant/Forward Rate Constant
Rate of Chemical Reaction
Go Rate of chemical reaction = Change in concentration/Total time interval
Rate Constant given Maximum Rate and Initial Enzyme Concentration
Go Final Rate Constant = Maximum Rate/Initial Enzyme Concentration

Reverse Rate Constant in Enzymatic Reaction Mechanism Formula

Reverse Rate Constant = (Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex Concentration
kr = (kf*S*([E0]-ES))/ES

What is Michaelis–Menten kinetics model?

In biochemistry, Michaelis–Menten kinetics is one of the best-known models of enzyme kinetics. Biochemical reactions involving a single substrate are often assumed to follow Michaelis–Menten kinetics, without regard to the model's underlying assumptions. The model takes the form of an equation describing the rate of enzymatic reactions, by relating the reaction rate of formation of product to the concentration of a substrate.

How to Calculate Reverse Rate Constant in Enzymatic Reaction Mechanism?

Reverse Rate Constant in Enzymatic Reaction Mechanism calculator uses Reverse Rate Constant = (Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex Concentration to calculate the Reverse Rate Constant, The Reverse rate constant in enzymatic reaction mechanism formula is defined as the relation with the rate constant of forward reaction and with the concentration of enzyme and substrate. Reverse Rate Constant is denoted by kr symbol.

How to calculate Reverse Rate Constant in Enzymatic Reaction Mechanism using this online calculator? To use this online calculator for Reverse Rate Constant in Enzymatic Reaction Mechanism, enter Forward Rate Constant (kf), Substrate Concentration (S), Initial Enzyme Concentration ([E0]) & Enzyme Substrate Complex Concentration (ES) and hit the calculate button. Here is how the Reverse Rate Constant in Enzymatic Reaction Mechanism calculation can be explained with given input values -> 0.09315 = (6.9*1500*(100000-10000))/10000.

FAQ

What is Reverse Rate Constant in Enzymatic Reaction Mechanism?
The Reverse rate constant in enzymatic reaction mechanism formula is defined as the relation with the rate constant of forward reaction and with the concentration of enzyme and substrate and is represented as kr = (kf*S*([E0]-ES))/ES or Reverse Rate Constant = (Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex Concentration. The Forward Rate Constant is defined as the rate constant for the forward occurring reaction, The Substrate Concentration is the number of moles of substrate per liter solution, The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction & The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate.
How to calculate Reverse Rate Constant in Enzymatic Reaction Mechanism?
The Reverse rate constant in enzymatic reaction mechanism formula is defined as the relation with the rate constant of forward reaction and with the concentration of enzyme and substrate is calculated using Reverse Rate Constant = (Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex Concentration. To calculate Reverse Rate Constant in Enzymatic Reaction Mechanism, you need Forward Rate Constant (kf), Substrate Concentration (S), Initial Enzyme Concentration ([E0]) & Enzyme Substrate Complex Concentration (ES). With our tool, you need to enter the respective value for Forward Rate Constant, Substrate Concentration, Initial Enzyme Concentration & Enzyme Substrate Complex Concentration and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Reverse Rate Constant?
In this formula, Reverse Rate Constant uses Forward Rate Constant, Substrate Concentration, Initial Enzyme Concentration & Enzyme Substrate Complex Concentration. We can use 3 other way(s) to calculate the same, which is/are as follows -
  • Reverse Rate Constant = (Dissociation Rate Constant*Forward Rate Constant)
  • Reverse Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Catalytic Rate Constant
  • Reverse Rate Constant = (Michaelis Constant*Forward Rate Constant)-Catalytic Rate Constant
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