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Anion Gap Formula

Anion Gap=Na-(Cl+HCO3)
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What is Anion Gap?

The anion gap (AG) is a measure of acid-base balance. Your body maintains balance by holding onto or releasing carbon dioxide through the lungs (acid) or bicarbonate through the kidneys (base). An anion gap can be high, normal, or low (rare). A high anion gap indicates the presence of more anions than cations, or acidosis. The normal value for the serum anion gap is approximately three to 10 mEq/L (averaging six mEq/L) but may vary according to your lab.

Anion Gap Causes and Symptoms

High anion gap acidosis may be caused by:ketoacidosis, lactic acidosis, renal failure, toxic ingestions while Normal anion gap acidosis may be caused by: gastrointestinal or renal bicarbonate losses, impaired renal excretion. While mild acidemia is typically asymptomatic, symptoms and signs of high anion gap acidosis may include: nausea, vomiting, malaise, hyperpnea (long, deep breaths at a normal rate), fatigue and cardiac dysfunction with hypotension, shock, ventricular arrhythmias .

How to Calculate Anion Gap?

Anion Gap calculator uses Anion Gap=Na-(Cl+HCO3) to calculate the Anion Gap, The anion gap is the difference in the measured cations (positively charged ions) and the measured anions (negatively charged ions) in serum, plasma, or urine. Anion Gap and is denoted by AG symbol.

How to calculate Anion Gap using this online calculator? To use this online calculator for Anion Gap, enter Na (Na), Cl (Cl) and HCO3 (HCO3) and hit the calculate button. Here is how the Anion Gap calculation can be explained with given input values -> 9 = 136-(100+27).

FAQ

What is Anion Gap?
The anion gap is the difference in the measured cations (positively charged ions) and the measured anions (negatively charged ions) in serum, plasma, or urine and is represented as AG=Na-(Cl+HCO3) or Anion Gap=Na-(Cl+HCO3). Sodium Ion is the ion which is formed when the sodium atom loses its outer electron, Chloride ion is the anion which is formed when the element chlorine gains an electron and Bicarbonate is an intermediate form in the deprotonation of carbonic acid.
How to calculate Anion Gap?
The anion gap is the difference in the measured cations (positively charged ions) and the measured anions (negatively charged ions) in serum, plasma, or urine is calculated using Anion Gap=Na-(Cl+HCO3). To calculate Anion Gap, you need Na (Na), Cl (Cl) and HCO3 (HCO3). With our tool, you need to enter the respective value for Na, Cl and HCO3 and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
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