What is Pharmacokinetics?
Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.
How to Calculate Area under Curve given Dose and Volume of Distribution?
Area under Curve given Dose and Volume of Distribution calculator uses Area Under Curve = Dose/(Volume of Distribution*Elimination Rate Constant) to calculate the Area Under Curve, The Area under Curve given Dose and Volume of Distribution formula is defined as the ratio amount of drug administered to the rate at which a drug is removed from the body with apparent volume in which a drug is distributed. Area Under Curve is denoted by AUC symbol.
How to calculate Area under Curve given Dose and Volume of Distribution using this online calculator? To use this online calculator for Area under Curve given Dose and Volume of Distribution, enter Dose (D), Volume of Distribution (V_{d}) & Elimination Rate Constant (k_{e}) and hit the calculate button. Here is how the Area under Curve given Dose and Volume of Distribution calculation can be explained with given input values -> 55172.41 = 8/(0.009*1.61111111111111E-05).