Bioavailability given Drug Purity Calculator

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Bioavailability

Area under curve

Dose

Drug Content

Drug Stability

Elimination Rate Constant

Isotonic Solutions

Plasma

Steady state Concentration

Volume of Distribution

Volume of plasma cleared

✖The Effective Dose is a dose or concentration of a drug that produces a biological response.ⓘ Effective Dose [D_e]			+10% -10%
✖The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.ⓘ Drug Purity [Q]			+10% -10%
✖Administered Dose is the amount of drug administered for a pharmacological response.ⓘ Administered Dose [D_a]			+10% -10%

✖The Bioavailability is the systemically available fraction of a drug.ⓘ Bioavailability given Drug Purity [B]

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Formula

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Bioavailability given Drug Purity

Formula

`"B" = "D"_{"e"}/("Q"*"D"_{"a"})`

Example

`"0.022774"="5.5µg"/("69"*"3.5µg")`

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Bioavailability given Drug Purity Solution

STEP 0: Pre-Calculation Summary

Formula Used

Bioavailability = Effective Dose/(Drug Purity*Administered Dose)
B = D_e/(Q*D_a)
This formula uses 4 Variables

Variables Used

Bioavailability - The Bioavailability is the systemically available fraction of a drug.
Effective Dose - (Measured in Kilogram) - The Effective Dose is a dose or concentration of a drug that produces a biological response.
Drug Purity - The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.
Administered Dose - (Measured in Kilogram) - Administered Dose is the amount of drug administered for a pharmacological response.

STEP 1: Convert Input(s) to Base Unit

Effective Dose: 5.5 Microgram --> 5.5E-09 Kilogram (Check conversion here)
Drug Purity: 69 --> No Conversion Required
Administered Dose: 3.5 Microgram --> 3.5E-09 Kilogram (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

B = D_e/(Q*D_a) --> 5.5E-09/(69*3.5E-09)

Evaluating ... ...

B = 0.0227743271221532

STEP 3: Convert Result to Output's Unit

0.0227743271221532 --> No Conversion Required

FINAL ANSWER

0.0227743271221532 ≈ 0.022774 <-- Bioavailability

(Calculation completed in 00.008 seconds)

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Created by Prashant Singh

K J Somaiya College of science (K J Somaiya), Mumbai

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< 4 Bioavailability Calculators

Bioavailability of Drug

Go Bioavailability of Drug = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Dose Non-Intravenous)

Bioavailability given Rate of Administration and Dosing Interval

Go Bioavailability = (Drug Rate of Administration*Dosing Interval)/(Administered Dose*Drug Purity)

Bioavailability given Drug Purity

Go Bioavailability = Effective Dose/(Drug Purity*Administered Dose)

Bioavailability given Effective and Administrative Dose

Go Bioavailability = Effective Dose/Administered Dose

Bioavailability given Drug Purity Formula

Bioavailability = Effective Dose/(Drug Purity*Administered Dose)
B = D_e/(Q*D_a)

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Bioavailability given Drug Purity?

Bioavailability given Drug Purity calculator uses Bioavailability = Effective Dose/(Drug Purity*Administered Dose) to calculate the Bioavailability, The Bioavailability given drug purity formula is defined as the ratio of the effective dose to the drug purity of the administered dose. Bioavailability is denoted by B symbol.

How to calculate Bioavailability given Drug Purity using this online calculator? To use this online calculator for Bioavailability given Drug Purity, enter Effective Dose (D_e), Drug Purity (Q) & Administered Dose (D_a) and hit the calculate button. Here is how the Bioavailability given Drug Purity calculation can be explained with given input values -> 0.022774 = 5.5E-09/(69*3.5E-09).

FAQ

What is Bioavailability given Drug Purity?

The Bioavailability given drug purity formula is defined as the ratio of the effective dose to the drug purity of the administered dose and is represented as B = D_e/(Q*D_a) or Bioavailability = Effective Dose/(Drug Purity*Administered Dose). The Effective Dose is a dose or concentration of a drug that produces a biological response, The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present & Administered Dose is the amount of drug administered for a pharmacological response.

How to calculate Bioavailability given Drug Purity?

The Bioavailability given drug purity formula is defined as the ratio of the effective dose to the drug purity of the administered dose is calculated using Bioavailability = Effective Dose/(Drug Purity*Administered Dose). To calculate Bioavailability given Drug Purity, you need Effective Dose (D_e), Drug Purity (Q) & Administered Dose (D_a). With our tool, you need to enter the respective value for Effective Dose, Drug Purity & Administered Dose and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Bioavailability?

In this formula, Bioavailability uses Effective Dose, Drug Purity & Administered Dose. We can use 2 other way(s) to calculate the same, which is/are as follows -

Bioavailability = Effective Dose/Administered Dose
Bioavailability = (Drug Rate of Administration*Dosing Interval)/(Administered Dose*Drug Purity)

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