Drug Loading Efficiency Calculator

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✖The Weight of drug in nanoparticles is the amount of the drug that has been successfully encapsulated or loaded into the nanoparticles.ⓘ Weight of drug in nanoparticles [WD_n]			+10% -10%
✖The Weight of the Nanoparticles is the total weight of the nanoparticles, which includes both the drug and any other materials used in the nanoparticle formulation.ⓘ Weight of the Nanoparticles [N_w]			+10% -10%

✖The Drug Loading Efficiency is a measure used in pharmaceutical and drug delivery research to quantify the amount of a specific drug that has been successfully loaded into a carrier system.ⓘ Drug Loading Efficiency [DLE%]

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Formula

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Drug Loading Efficiency

Formula

`"DLE%" = "WD"_{"n"}/"N"_{"w"}*100`

Example

`"25"="5mg"/"20mg"*100`

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Drug Loading Efficiency Solution

STEP 0: Pre-Calculation Summary

Formula Used

Drug Loading Efficiency = Weight of drug in nanoparticles/Weight of the Nanoparticles*100
DLE% = WD_n/N_w*100
This formula uses 3 Variables

Variables Used

Drug Loading Efficiency - The Drug Loading Efficiency is a measure used in pharmaceutical and drug delivery research to quantify the amount of a specific drug that has been successfully loaded into a carrier system.
Weight of drug in nanoparticles - (Measured in Kilogram) - The Weight of drug in nanoparticles is the amount of the drug that has been successfully encapsulated or loaded into the nanoparticles.
Weight of the Nanoparticles - (Measured in Kilogram) - The Weight of the Nanoparticles is the total weight of the nanoparticles, which includes both the drug and any other materials used in the nanoparticle formulation.

STEP 1: Convert Input(s) to Base Unit

Weight of drug in nanoparticles: 5 Milligram --> 5E-06 Kilogram (Check conversion here)
Weight of the Nanoparticles: 20 Milligram --> 2E-05 Kilogram (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

DLE% = WD_n/N_w*100 --> 5E-06/2E-05*100

Evaluating ... ...

DLE% = 25

STEP 3: Convert Result to Output's Unit

25 --> No Conversion Required

FINAL ANSWER

25 <-- Drug Loading Efficiency

(Calculation completed in 00.005 seconds)

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Created by swapnalijadhav

idealinstituteofpharmacy (iip), Maharashtra

swapnalijadhav has created this Calculator and 10+ more calculators!

Verified by Soupayan banerjee

National University of Judicial Science (NUJS), Kolkata

Soupayan banerjee has verified this Calculator and 800+ more calculators!

< 25 Drug Content Calculators

Saponification value

Go Saponification Value = Molecular weight of KOH*(Volume of blank-Volume of Actual solution)*Normality of solution/Weight of sample taken

Fraction of Drug Unbound in Tissue given Apparent Tissue Volume

Go Fraction Unbound in Tissue = (Fraction Unbound in Plasma*Apparent Tissue Volume)/(Volume of Distribution-Plasma Volume)

Secretion Rate of Drug

Go Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug)

Reabsorption Rate of Drug

Go Reabsorption Rate of Drug = ((Renal Clearance*Plasma Concentration)+Filtration Rate+Secretion Rate of Drug)

Filtration Rate of Drug

Go Filtration Rate = ((Renal Clearance*Plasma Concentration)+Reabsorption Rate of Drug-Secretion Rate of Drug)

Relative Bioavailability of Drug

Go Relative Bioavailability = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Dose Type A)

Acid Value of KOH

Go Acid Value = Molecular weight of KOH*Volume of solution koh*Normality of solution/Weight of sample taken

Drug Purity given Rate of Administration and Dosing Interval

Go Drug Purity = (Drug Rate*Dosing Interval)/(Administered Dose*Bioavailability)

Rate of Administration of Drug given Dosing Interval

Go Drug Rate = (Administered Dose*Bioavailability*Drug Purity)/Dosing Interval

Drug Purity given Administrative Dose and Effective Dose

Go Drug Purity = Effective Dose/(Administered Dose*Bioavailability)

Drug Loading Efficiency

Go Drug Loading Efficiency = Weight of drug in nanoparticles/Weight of the Nanoparticles*100

Encapsulation Efficiency

Go Encapsulation Efficiency = Weight of drug in nanoparticles/Weight of feeding drug*100

Renal Clearance of Drug

Go Renal Clearance = Drug Amount Excreted Unchanged in Urine/Area Under Curve

Concentration of Drug given Rate of Infusion of Drug

Go Concentration of Drug = Rate of Infusion/Volume of Plasma Cleared

Rate of Infusion of Drug

Go Rate of Infusion = Volume of Plasma Cleared*Concentration of Drug

Median Lethal Dose using Therapeutic Index

Go Median Lethal Dose = (Median Effective Dose*Therapeutic Index)

Margin of Safety of Drugs

Go Margin of Safety = Toxic Dose Response/Effective Dose Response

Effective Dose using Therapeutic Index

Go Median Effective Dose = Median Lethal Dose/Therapeutic Index

Therapeutic Index

Go Therapeutic Index = Median Lethal Dose/Median Effective Dose

Absorption Half-Life of Drug

Go Absorption Half Life = ln(2)/Absorption Rate Constant

Drug Rate Entering Body

Go Absorption Rate Constant = ln(2)/Absorption Half Life

Concentration of Drug using Volume of Distribution

Go Concentration of Drug = Dose/Volume of Distribution

Apparent Volume of Drug Distribution

Go Volume of Distribution = Dose/Concentration of Drug

Tablet Dosage

Go Number of tablet = Desired dosage/Stock strength

Easter Value

Go Easter Value = Saponification Value-Acid Value

Drug Loading Efficiency Formula

Drug Loading Efficiency = Weight of drug in nanoparticles/Weight of the Nanoparticles*100
DLE% = WD_n/N_w*100

What is drug loading efficiency?

The Drug Loading Efficiency is a measure used in pharmaceutical and drug delivery research to quantify the amount of a specific drug that has been successfully loaded into a carrier system.

How to Calculate Drug Loading Efficiency?

Drug Loading Efficiency calculator uses Drug Loading Efficiency = Weight of drug in nanoparticles/Weight of the Nanoparticles*100 to calculate the Drug Loading Efficiency, The Drug loading efficiency formula is defined as a measure used in pharmaceutical and drug delivery research to quantify the amount of a specific drug that has been successfully loaded into a carrier system. Drug Loading Efficiency is denoted by DLE% symbol.

How to calculate Drug Loading Efficiency using this online calculator? To use this online calculator for Drug Loading Efficiency, enter Weight of drug in nanoparticles (WD_n) & Weight of the Nanoparticles (N_w) and hit the calculate button. Here is how the Drug Loading Efficiency calculation can be explained with given input values -> 25 = 5E-06/2E-05*100.

FAQ

What is Drug Loading Efficiency?

The Drug loading efficiency formula is defined as a measure used in pharmaceutical and drug delivery research to quantify the amount of a specific drug that has been successfully loaded into a carrier system and is represented as DLE% = WD_n/N_w*100 or Drug Loading Efficiency = Weight of drug in nanoparticles/Weight of the Nanoparticles*100. The Weight of drug in nanoparticles is the amount of the drug that has been successfully encapsulated or loaded into the nanoparticles & The Weight of the Nanoparticles is the total weight of the nanoparticles, which includes both the drug and any other materials used in the nanoparticle formulation.

How to calculate Drug Loading Efficiency?

The Drug loading efficiency formula is defined as a measure used in pharmaceutical and drug delivery research to quantify the amount of a specific drug that has been successfully loaded into a carrier system is calculated using Drug Loading Efficiency = Weight of drug in nanoparticles/Weight of the Nanoparticles*100. To calculate Drug Loading Efficiency, you need Weight of drug in nanoparticles (WD_n) & Weight of the Nanoparticles (N_w). With our tool, you need to enter the respective value for Weight of drug in nanoparticles & Weight of the Nanoparticles and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

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