Drug Purity given Administrative Dose and Effective Dose Solution

STEP 0: Pre-Calculation Summary
Formula Used
Drug Purity = Effective Dose/(Administered Dose*Bioavailability)
Q = De/(Da*B)
This formula uses 4 Variables
Variables Used
Drug Purity - The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.
Effective Dose - (Measured in Kilogram) - The Effective Dose is a dose or concentration of a drug that produces a biological response.
Administered Dose - (Measured in Kilogram) - Administered Dose is the amount of drug administered for a pharmacological response.
Bioavailability - The Bioavailability is the systemically available fraction of a drug.
STEP 1: Convert Input(s) to Base Unit
Effective Dose: 5.5 Microgram --> 5.5E-09 Kilogram (Check conversion here)
Administered Dose: 3.5 Microgram --> 3.5E-09 Kilogram (Check conversion here)
Bioavailability: 12.5 --> No Conversion Required
STEP 2: Evaluate Formula
Substituting Input Values in Formula
Q = De/(Da*B) --> 5.5E-09/(3.5E-09*12.5)
Evaluating ... ...
Q = 0.125714285714286
STEP 3: Convert Result to Output's Unit
0.125714285714286 --> No Conversion Required
0.125714285714286 <-- Drug Purity
(Calculation completed in 00.000 seconds)
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Created by Prashant Singh
K J Somaiya College of science (K J Somaiya), Mumbai
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Secretion Rate of Drug
Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug)
Reabsorption Rate of Drug
Reabsorption Rate of Drug = ((-Renal Clearance*Plasma Concentration)+Filtration Rate+Secretion Rate of Drug)
Filtration Rate of Drug
Filtration Rate = ((Renal Clearance*Plasma Concentration)+Reabsorption Rate of Drug-Secretion Rate of Drug)
Relative Bioavailability of Drug
Relative Bioavailability = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Dose Type A)
Drug Purity given Rate of Administration and Dosing Interval
Rate of Administration of Drug given Dosing Interval
Drug Purity given Administrative Dose and Effective Dose
Drug Purity = Effective Dose/(Administered Dose*Bioavailability)
Renal Clearance of Drug
Renal Clearance = Drug Amount Excreted Unchanged in Urine/Area Under Curve
Concentration of Drug given Rate of Infusion of Drug
Concentration of Drug = Rate of Infusion/Volume of Plasma Cleared
Rate of Infusion of Drug
Rate of Infusion = Volume of Plasma Cleared*Concentration of Drug
Absorption Half-Life of Drug
Absorption Half Life = ln(2)/Absorption Rate Constant
Drug Rate Entering Body
Absorption Rate Constant = ln(2)/Absorption Half Life
Apparent Volume of Drug Distribution
Volume of Distribution = Dose/Concentration of Drug

Drug Purity given Administrative Dose and Effective Dose Formula

Drug Purity = Effective Dose/(Administered Dose*Bioavailability)
Q = De/(Da*B)

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Drug Purity given Administrative Dose and Effective Dose?

Drug Purity given Administrative Dose and Effective Dose calculator uses Drug Purity = Effective Dose/(Administered Dose*Bioavailability) to calculate the Drug Purity, The Drug purity given Administrative dose and Effective dose formula is defined as the ratio of the effective dose to the administered dose and bioavailability of the particular drug. Drug Purity is denoted by Q symbol.

How to calculate Drug Purity given Administrative Dose and Effective Dose using this online calculator? To use this online calculator for Drug Purity given Administrative Dose and Effective Dose, enter Effective Dose (De), Administered Dose (Da) & Bioavailability (B) and hit the calculate button. Here is how the Drug Purity given Administrative Dose and Effective Dose calculation can be explained with given input values -> 0.125714 = 5.5E-09/(3.5E-09*12.5).

FAQ

What is Drug Purity given Administrative Dose and Effective Dose?
The Drug purity given Administrative dose and Effective dose formula is defined as the ratio of the effective dose to the administered dose and bioavailability of the particular drug and is represented as Q = De/(Da*B) or Drug Purity = Effective Dose/(Administered Dose*Bioavailability). The Effective Dose is a dose or concentration of a drug that produces a biological response, Administered Dose is the amount of drug administered for a pharmacological response & The Bioavailability is the systemically available fraction of a drug.
How to calculate Drug Purity given Administrative Dose and Effective Dose?
The Drug purity given Administrative dose and Effective dose formula is defined as the ratio of the effective dose to the administered dose and bioavailability of the particular drug is calculated using Drug Purity = Effective Dose/(Administered Dose*Bioavailability). To calculate Drug Purity given Administrative Dose and Effective Dose, you need Effective Dose (De), Administered Dose (Da) & Bioavailability (B). With our tool, you need to enter the respective value for Effective Dose, Administered Dose & Bioavailability and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Drug Purity?
In this formula, Drug Purity uses Effective Dose, Administered Dose & Bioavailability. We can use 1 other way(s) to calculate the same, which is/are as follows -