Drug Purity given Rate of Administration and Dosing Interval Solution

STEP 0: Pre-Calculation Summary
Formula Used
Drug Purity = (Drug Rate*Dosing Interval)/(Administered Dose*Bioavailability)
Q = (Vadmin*Τ)/(Da*B)
This formula uses 5 Variables
Variables Used
Drug Purity - The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.
Drug Rate - (Measured in Kilogram per Second) - Drug Rate of Administration is the amount of drug administered in a particular interval of time.
Dosing Interval - (Measured in Second) - The Dosing Interval is the time between drug dose administrations.
Administered Dose - (Measured in Kilogram) - Administered Dose is the amount of drug administered for a pharmacological response.
Bioavailability - The Bioavailability is the systemically available fraction of a drug.
STEP 1: Convert Input(s) to Base Unit
Drug Rate: 45 Kilogram per Second --> 45 Kilogram per Second No Conversion Required
Dosing Interval: 44 Second --> 44 Second No Conversion Required
Administered Dose: 3.5 Microgram --> 3.5E-09 Kilogram (Check conversion here)
Bioavailability: 12.5 --> No Conversion Required
STEP 2: Evaluate Formula
Substituting Input Values in Formula
Q = (Vadmin*Τ)/(Da*B) --> (45*44)/(3.5E-09*12.5)
Evaluating ... ...
Q = 45257142857.1429
STEP 3: Convert Result to Output's Unit
45257142857.1429 --> No Conversion Required
FINAL ANSWER
45257142857.1429 4.5E+10 <-- Drug Purity
(Calculation completed in 00.020 seconds)

Credits

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K J Somaiya College of science (K J Somaiya), Mumbai
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25 Drug Content Calculators

Saponification value
Go Saponification Value = Molecular weight of KOH*(Volume of blank-Volume of Actual solution)*Normality of solution/Weight of sample taken
Fraction of Drug Unbound in Tissue given Apparent Tissue Volume
Go Fraction Unbound in Tissue = (Fraction Unbound in Plasma*Apparent Tissue Volume)/(Volume of Distribution-Plasma Volume)
Secretion Rate of Drug
Go Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug)
Reabsorption Rate of Drug
Go Reabsorption Rate of Drug = ((Renal Clearance*Plasma Concentration)+Filtration Rate+Secretion Rate of Drug)
Filtration Rate of Drug
Go Filtration Rate = ((Renal Clearance*Plasma Concentration)+Reabsorption Rate of Drug-Secretion Rate of Drug)
Relative Bioavailability of Drug
Go Relative Bioavailability = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Dose Type A)
Acid Value of KOH
Go Acid Value = Molecular weight of KOH*Volume of solution koh*Normality of solution/Weight of sample taken
Drug Purity given Rate of Administration and Dosing Interval
Go Drug Purity = (Drug Rate*Dosing Interval)/(Administered Dose*Bioavailability)
Rate of Administration of Drug given Dosing Interval
Go Drug Rate = (Administered Dose*Bioavailability*Drug Purity)/Dosing Interval
Drug Purity given Administrative Dose and Effective Dose
Go Drug Purity = Effective Dose/(Administered Dose*Bioavailability)
Drug Loading Efficiency
Go Drug Loading Efficiency = Weight of drug in nanoparticles/Weight of the Nanoparticles*100
Encapsulation Efficiency
Go Encapsulation Efficiency = Weight of drug in nanoparticles/Weight of feeding drug*100
Renal Clearance of Drug
Go Renal Clearance = Drug Amount Excreted Unchanged in Urine/Area Under Curve
Concentration of Drug given Rate of Infusion of Drug
Go Concentration of Drug = Rate of Infusion/Volume of Plasma Cleared
Rate of Infusion of Drug
Go Rate of Infusion = Volume of Plasma Cleared*Concentration of Drug
Median Lethal Dose using Therapeutic Index
Go Median Lethal Dose = (Median Effective Dose*Therapeutic Index)
Margin of Safety of Drugs
Go Margin of Safety = Toxic Dose Response/Effective Dose Response
Effective Dose using Therapeutic Index
Go Median Effective Dose = Median Lethal Dose/Therapeutic Index
Therapeutic Index
Go Therapeutic Index = Median Lethal Dose/Median Effective Dose
Absorption Half-Life of Drug
Go Absorption Half Life = ln(2)/Absorption Rate Constant
Drug Rate Entering Body
Go Absorption Rate Constant = ln(2)/Absorption Half Life
Concentration of Drug using Volume of Distribution
Go Concentration of Drug = Dose/Volume of Distribution
Apparent Volume of Drug Distribution
Go Volume of Distribution = Dose/Concentration of Drug
Tablet Dosage
Go Number of tablet = Desired dosage/Stock strength
Easter Value
Go Easter Value = Saponification Value-Acid Value

Drug Purity given Rate of Administration and Dosing Interval Formula

Drug Purity = (Drug Rate*Dosing Interval)/(Administered Dose*Bioavailability)
Q = (Vadmin*Τ)/(Da*B)

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Drug Purity given Rate of Administration and Dosing Interval?

Drug Purity given Rate of Administration and Dosing Interval calculator uses Drug Purity = (Drug Rate*Dosing Interval)/(Administered Dose*Bioavailability) to calculate the Drug Purity, The Drug purity given rate of administration and dosing interval formula is defined as the ratio of the rate of administration of the drug with dosing interval to the administrative dose and a systemically available fraction of a drug. Drug Purity is denoted by Q symbol.

How to calculate Drug Purity given Rate of Administration and Dosing Interval using this online calculator? To use this online calculator for Drug Purity given Rate of Administration and Dosing Interval, enter Drug Rate (Vadmin), Dosing Interval (Τ), Administered Dose (Da) & Bioavailability (B) and hit the calculate button. Here is how the Drug Purity given Rate of Administration and Dosing Interval calculation can be explained with given input values -> 4.5E+10 = (45*44)/(3.5E-09*12.5).

FAQ

What is Drug Purity given Rate of Administration and Dosing Interval?
The Drug purity given rate of administration and dosing interval formula is defined as the ratio of the rate of administration of the drug with dosing interval to the administrative dose and a systemically available fraction of a drug and is represented as Q = (Vadmin*Τ)/(Da*B) or Drug Purity = (Drug Rate*Dosing Interval)/(Administered Dose*Bioavailability). Drug Rate of Administration is the amount of drug administered in a particular interval of time, The Dosing Interval is the time between drug dose administrations, Administered Dose is the amount of drug administered for a pharmacological response & The Bioavailability is the systemically available fraction of a drug.
How to calculate Drug Purity given Rate of Administration and Dosing Interval?
The Drug purity given rate of administration and dosing interval formula is defined as the ratio of the rate of administration of the drug with dosing interval to the administrative dose and a systemically available fraction of a drug is calculated using Drug Purity = (Drug Rate*Dosing Interval)/(Administered Dose*Bioavailability). To calculate Drug Purity given Rate of Administration and Dosing Interval, you need Drug Rate (Vadmin), Dosing Interval (Τ), Administered Dose (Da) & Bioavailability (B). With our tool, you need to enter the respective value for Drug Rate, Dosing Interval, Administered Dose & Bioavailability and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Drug Purity?
In this formula, Drug Purity uses Drug Rate, Dosing Interval, Administered Dose & Bioavailability. We can use 1 other way(s) to calculate the same, which is/are as follows -
  • Drug Purity = Effective Dose/(Administered Dose*Bioavailability)
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