What is Pharmacokinetics?
Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.
How to Calculate Elimination Half Life given Volume of Plasma Cleared?
Elimination Half Life given Volume of Plasma Cleared calculator uses Elimination Half Life = (ln(2)*Volume of Distribution)/Volume of Plasma Cleared to calculate the Elimination Half Life, The Elimination half life given volume of plasma cleared formula is defined as the direct relation with the apparent volume in which a drug is distributed and an inverse relationship with the volume of plasma cleared of the drug per unit time. Elimination Half Life is denoted by t_{b/2} symbol.
How to calculate Elimination Half Life given Volume of Plasma Cleared using this online calculator? To use this online calculator for Elimination Half Life given Volume of Plasma Cleared, enter Volume of Distribution (V_{d}) & Volume of Plasma Cleared (CL) and hit the calculate button. Here is how the Elimination Half Life given Volume of Plasma Cleared calculation can be explained with given input values -> 12.99651 = (ln(2)*0.009)/0.00048.