## Elimination Half Life given Volume of Plasma Cleared Solution

STEP 0: Pre-Calculation Summary
Formula Used
Elimination Half Life = (ln(2)*Volume of Distribution)/Volume of Plasma Cleared
tb/2 = (ln(2)*Vd)/CL
This formula uses 1 Functions, 3 Variables
Functions Used
ln - Natural logarithm function (base e), ln(Number)
Variables Used
Elimination Half Life - (Measured in Second) - Elimination Half Life is the time required for the concentration of the drug to reach half of its original value.
Volume of Distribution - (Measured in Cubic Meter) - The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.
Volume of Plasma Cleared - (Measured in Cubic Meter per Second) - The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.
STEP 1: Convert Input(s) to Base Unit
Volume of Distribution: 9 Liter --> 0.009 Cubic Meter (Check conversion here)
Volume of Plasma Cleared: 0.48 Liter per Second --> 0.00048 Cubic Meter per Second (Check conversion here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
tb/2 = (ln(2)*Vd)/CL --> (ln(2)*0.009)/0.00048
Evaluating ... ...
tb/2 = 12.996509635499
STEP 3: Convert Result to Output's Unit
12.996509635499 Second --> No Conversion Required
12.996509635499 Second <-- Elimination Half Life
(Calculation completed in 00.015 seconds)
You are here -
Home »

## Credits

Created by Prashant Singh
K J Somaiya College of science (K J Somaiya), Mumbai
Prashant Singh has created this Calculator and 700+ more calculators!
Verified by Prerana Bakli
National Institute of Technology (NIT), Meghalaya
Prerana Bakli has verified this Calculator and 1300+ more calculators!

## < 5 Elimination Rate Constant Calculators

Elimination Half Life given Volume of Plasma Cleared
Elimination Half Life = (ln(2)*Volume of Distribution)/Volume of Plasma Cleared
Elimination Rate Constant given Area under Curve
Elimination Rate Constant = Dose/(Area Under Curve*Volume of Distribution)
Elimination Rate Constant given Volume of Plasma Cleared
Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution
Elimination Rate Constant of Drug
Elimination Rate Constant = ln(2)/Elimination Half Life
Elimination Half Life of Drug
Elimination Half Life = ln(2)/Elimination Rate Constant

## Elimination Half Life given Volume of Plasma Cleared Formula

Elimination Half Life = (ln(2)*Volume of Distribution)/Volume of Plasma Cleared
tb/2 = (ln(2)*Vd)/CL

## What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

## How to Calculate Elimination Half Life given Volume of Plasma Cleared?

Elimination Half Life given Volume of Plasma Cleared calculator uses Elimination Half Life = (ln(2)*Volume of Distribution)/Volume of Plasma Cleared to calculate the Elimination Half Life, The Elimination half life given volume of plasma cleared formula is defined as the direct relation with the apparent volume in which a drug is distributed and an inverse relationship with the volume of plasma cleared of the drug per unit time. Elimination Half Life is denoted by tb/2 symbol.

How to calculate Elimination Half Life given Volume of Plasma Cleared using this online calculator? To use this online calculator for Elimination Half Life given Volume of Plasma Cleared, enter Volume of Distribution (Vd) & Volume of Plasma Cleared (CL) and hit the calculate button. Here is how the Elimination Half Life given Volume of Plasma Cleared calculation can be explained with given input values -> 12.99651 = (ln(2)*0.009)/0.00048.

### FAQ

What is Elimination Half Life given Volume of Plasma Cleared?
The Elimination half life given volume of plasma cleared formula is defined as the direct relation with the apparent volume in which a drug is distributed and an inverse relationship with the volume of plasma cleared of the drug per unit time and is represented as tb/2 = (ln(2)*Vd)/CL or Elimination Half Life = (ln(2)*Volume of Distribution)/Volume of Plasma Cleared. The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body & The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.
How to calculate Elimination Half Life given Volume of Plasma Cleared?
The Elimination half life given volume of plasma cleared formula is defined as the direct relation with the apparent volume in which a drug is distributed and an inverse relationship with the volume of plasma cleared of the drug per unit time is calculated using Elimination Half Life = (ln(2)*Volume of Distribution)/Volume of Plasma Cleared. To calculate Elimination Half Life given Volume of Plasma Cleared, you need Volume of Distribution (Vd) & Volume of Plasma Cleared (CL). With our tool, you need to enter the respective value for Volume of Distribution & Volume of Plasma Cleared and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Elimination Half Life?
In this formula, Elimination Half Life uses Volume of Distribution & Volume of Plasma Cleared. We can use 1 other way(s) to calculate the same, which is/are as follows -
• Elimination Half Life = ln(2)/Elimination Rate Constant Let Others Know