What is Pharmacokinetics?
Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.
How to Calculate Elimination Rate Constant given Volume of Plasma Cleared?
Elimination Rate Constant given Volume of Plasma Cleared calculator uses Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution to calculate the Elimination Rate Constant, The Elimination rate constant given volume of plasma cleared formula is defined as the ratio of the volume of plasma cleared of the drug per unit time to the apparent volume in which a drug is distributed. Elimination Rate Constant is denoted by k_{e} symbol.
How to calculate Elimination Rate Constant given Volume of Plasma Cleared using this online calculator? To use this online calculator for Elimination Rate Constant given Volume of Plasma Cleared, enter Volume of Plasma Cleared (CL) & Volume of Distribution (V_{d}) and hit the calculate button. Here is how the Elimination Rate Constant given Volume of Plasma Cleared calculation can be explained with given input values -> 192 = 0.00048/0.009.