Initial Reaction Rate given Dissociation Rate Constant Solution

STEP 0: Pre-Calculation Summary
Formula Used
Initial Reaction Rate given DRC = (Maximum Rate*Substrate Concentration)/(Dissociation Rate Constant+Substrate Concentration)
VDRC = (Vmax*S)/(KD+S)
This formula uses 4 Variables
Variables Used
Initial Reaction Rate given DRC - (Measured in Mole per Cubic Meter Second) - Initial Reaction Rate given DRC is defined as the initial speed at which a chemical reaction takes place.
Maximum Rate - (Measured in Mole per Cubic Meter Second) - The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration.
Substrate Concentration - (Measured in Mole per Cubic Meter) - The Substrate Concentration is the number of moles of substrate per liter solution.
Dissociation Rate Constant - (Measured in Mole per Cubic Meter) - The Dissociation Rate Constant is the ratio of reverse and forward rate constant.
STEP 1: Convert Input(s) to Base Unit
Maximum Rate: 40 Mole per Liter Second --> 40000 Mole per Cubic Meter Second (Check conversion here)
Substrate Concentration: 1.5 Mole per Liter --> 1500 Mole per Cubic Meter (Check conversion here)
Dissociation Rate Constant: 5.7 Mole per Liter --> 5700 Mole per Cubic Meter (Check conversion here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
VDRC = (Vmax*S)/(KD+S) --> (40000*1500)/(5700+1500)
Evaluating ... ...
VDRC = 8333.33333333333
STEP 3: Convert Result to Output's Unit
8333.33333333333 Mole per Cubic Meter Second -->8.33333333333333 Mole per Liter Second (Check conversion here)
FINAL ANSWER
8.33333333333333 8.333333 Mole per Liter Second <-- Initial Reaction Rate given DRC
(Calculation completed in 00.004 seconds)

Credits

Created by Prashant Singh
K J Somaiya College of science (K J Somaiya), Mumbai
Prashant Singh has created this Calculator and 700+ more calculators!
Verified by Prerana Bakli
University of Hawaiʻi at Mānoa (UH Manoa), Hawaii, USA
Prerana Bakli has verified this Calculator and 1600+ more calculators!

13 Enzyme Kinetics Calculators

Initial Reaction Rate given Catalytic Rate Constant and Dissociation Rate Constants
Go Initial Reaction Rate = (Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/(Dissociation Rate Constant+Substrate Concentration)
Initial Reaction Rate given Catalytic Rate Constant and Initial Enzyme Concentration
Go Initial Reaction Rate = (Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/(Michaelis Constant+Substrate Concentration)
Initial Reaction Rate given Dissociation Rate Constant
Go Initial Reaction Rate given DRC = (Maximum Rate*Substrate Concentration)/(Dissociation Rate Constant+Substrate Concentration)
Maximum Rate given Dissociation Rate Constant
Go Maximum Rate given DRC = (Initial Reaction Rate*(Dissociation Rate Constant+Substrate Concentration))/Substrate Concentration
Initial Reaction Rate at Low Substrate Concentration
Go Initial Reaction Rate = (Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Michaelis Constant
Initial Reaction Rate in Michaelis Menten kinetics Equation
Go Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/(Michaelis Constant+Substrate Concentration)
Initial Reaction Rate at Low Substrate Concentration terms of Maximum Rate
Go Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/Michaelis Constant
Maximum Rate of System at Low Substrate Concentration
Go Maximum Rate = (Initial Reaction Rate*Michaelis Constant)/Substrate Concentration
Modifying Factor of Enzyme Substrate Complex
Go Enzyme Substrate Modifying Factor = 1+(Inhibitor Concentration/Enzyme Substrate Dissociation Constant)
Initial Rate of System given Rate Constant and Enzyme Substrate Complex Concentration
Go Initial Reaction Rate given RC = Final Rate Constant*Enzyme Substrate Complex Concentration
Maximum Rate given Rate Constant and Initial Enzyme Concentration
Go Maximum Rate = (Final Rate Constant*Initial Enzyme Concentration)
Total Change in Concentration of Reaction
Go Total change in concentration = Average rate*Total time interval
Total Time taken during Reaction
Go Total time interval = Total change in concentration/Average rate

25 Important Formulas on Enzyme Kinetics Calculators

Final Rate Constant for Competitive Inhibition of Enzyme Catalysis
Go Final Rate Constant for Catalysis = (Initial Reaction Rate*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))+Substrate Concentration))/(Initial Enzyme Concentration*Substrate Concentration)
Inhibitor Concentration for Competitive Inhibition of Enzyme Catalysis
Go Inhibitor Concentration given IEC = (((((Final Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration)/Michaelis Constant)-1)*Enzyme Inhibitor Dissociation Constant
Michaelis Constant in Competitive Inhibition given Enzyme Substrate Complex Concentration
Go Michaelis Constant = (((Initial Enzyme Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Substrate Concentration)/(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))
Enzyme Substrate Complex Concentration for Competitive Inhibition of Enzyme Catalysis
Go Enzyme Substrate Complex Concentration = (Substrate Concentration*Initial Enzyme Concentration)/(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))+Substrate Concentration)
Inhibitor Concentration in Competitive Inhibition given Maximum Rate of System
Go Inhibitor Concentration given Max Rate = (((((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration)/Michaelis Constant)-1)*Enzyme Inhibitor Dissociation Constant
Initial Rate in Competitive Inhibition given Maximum Rate of system
Go Initial Reaction Rate in CI = (Maximum Rate*Substrate Concentration)/(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))+Substrate Concentration)
Enzyme Catalyst Concentration given Forward, Reverse, and Catalytic Rate Constants
Go Catalyst Concentration = ((Reverse Rate Constant+Catalytic Rate Constant)*Enzyme Substrate Complex Concentration)/(Forward Rate Constant*Substrate Concentration)
Catalytic Rate Constant from Michaelis Menten Kinetics Equation
Go Catalytic Rate Constant for MM = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/(Initial Enzyme Concentration*Substrate Concentration)
Enzyme Concentration from Michaelis Menten Kinetics equation
Go Initial Concentration of Enzyme = (Initial Reaction Rate*(Michaelis Constant+Substrate Concentration))/(Catalytic Rate Constant*Substrate Concentration)
Substrate Concentration given Catalytic Rate Constant and Initial Enzyme Concentration
Go Concentration of Substrate = (Michaelis Constant*Initial Reaction Rate)/((Catalytic Rate Constant*Initial Enzyme Concentration)-Initial Reaction Rate)
Initial Enzyme Concentration given Dissociation Rate Constant
Go Enzyme Concentration Initially = (Enzyme Substrate Complex Concentration*(Dissociation Rate Constant+Substrate Concentration))/(Substrate Concentration)
Initial Reaction Rate given Dissociation Rate Constant
Go Initial Reaction Rate given DRC = (Maximum Rate*Substrate Concentration)/(Dissociation Rate Constant+Substrate Concentration)
Maximum Rate given Dissociation Rate Constant
Go Maximum Rate given DRC = (Initial Reaction Rate*(Dissociation Rate Constant+Substrate Concentration))/Substrate Concentration
Inhibitor Concentration given Apparent Initial Enzyme Concentration
Go Inhibitor Concentration for CI = ((Initial Enzyme Concentration/Apparent Initial Enzyme Concentration)-1)*Enzyme Inhibitor Dissociation Constant
Initial Concentration of Enzyme in presence of Inhibitor by Enzyme Conservation Law
Go Enzyme Concentration Initially = (Catalyst Concentration+Enzyme Substrate Complex Concentration+Enzyme Inhibitor Complex Concentration)
Michaelis Constant given Forward, Reverse, and Catalytic Rate Constants
Go Michaelis Constant = (Reverse Rate Constant+Catalytic Rate Constant)/Forward Rate Constant
Inhibitor Concentration given Enzyme Substrate Modifying Factor
Go Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant
Modifying Factor of Enzyme Substrate Complex
Go Enzyme Substrate Modifying Factor = 1+(Inhibitor Concentration/Enzyme Substrate Dissociation Constant)
Dissociation Constant of Enzyme given Modifying Factor of Enzyme
Go Enzyme Inhibitor Dissociation Constant given MF = Inhibitor Concentration/(Enzyme Modifying Factor-1)
Initial Rate of System given Rate Constant and Enzyme Substrate Complex Concentration
Go Initial Reaction Rate given RC = Final Rate Constant*Enzyme Substrate Complex Concentration
Forward Rate Constant given Dissociation Rate Constant
Go Forward Rate Constant = (Reverse Rate Constant/Dissociation Rate Constant)
Dissociation Rate Constant in Enzymatic Reaction Mechanism
Go Dissociation Rate Constant = Reverse Rate Constant/Forward Rate Constant
Initial Enzyme Concentration if Substrate Concentration is Higher than Michaelis Constant
Go Enzyme Concentration Initially = Maximum Rate/Catalytic Rate Constant
Catalytic Rate Constant if Substrate Concentration is higher than Michaelis Constant
Go Catalytic Rate Constant = Maximum Rate/Initial Enzyme Concentration
Maximum Rate if Substrate Concentration is Higher than Michaelis Constant
Go Maximum Rate = Catalytic Rate Constant*Initial Enzyme Concentration

Initial Reaction Rate given Dissociation Rate Constant Formula

Initial Reaction Rate given DRC = (Maximum Rate*Substrate Concentration)/(Dissociation Rate Constant+Substrate Concentration)
VDRC = (Vmax*S)/(KD+S)

What is Michaelis–Menten kinetics model?

In biochemistry, Michaelis–Menten kinetics is one of the best-known models of enzyme kinetics. Biochemical reactions involving a single substrate are often assumed to follow Michaelis–Menten kinetics, without regard to the model's underlying assumptions. The model takes the form of an equation describing the rate of enzymatic reactions, by relating the reaction rate of formation of product to the concentration of a substrate.

How to Calculate Initial Reaction Rate given Dissociation Rate Constant?

Initial Reaction Rate given Dissociation Rate Constant calculator uses Initial Reaction Rate given DRC = (Maximum Rate*Substrate Concentration)/(Dissociation Rate Constant+Substrate Concentration) to calculate the Initial Reaction Rate given DRC, The Initial reaction rate given dissociation rate constant formula is defined as the relation with the maximum rate achieved by the system and the substrate concentration. Initial Reaction Rate given DRC is denoted by VDRC symbol.

How to calculate Initial Reaction Rate given Dissociation Rate Constant using this online calculator? To use this online calculator for Initial Reaction Rate given Dissociation Rate Constant, enter Maximum Rate (Vmax), Substrate Concentration (S) & Dissociation Rate Constant (KD) and hit the calculate button. Here is how the Initial Reaction Rate given Dissociation Rate Constant calculation can be explained with given input values -> 0.008333 = (40000*1500)/(5700+1500).

FAQ

What is Initial Reaction Rate given Dissociation Rate Constant?
The Initial reaction rate given dissociation rate constant formula is defined as the relation with the maximum rate achieved by the system and the substrate concentration and is represented as VDRC = (Vmax*S)/(KD+S) or Initial Reaction Rate given DRC = (Maximum Rate*Substrate Concentration)/(Dissociation Rate Constant+Substrate Concentration). The Maximum Rate is defined as the maximum speed achieved by the system at saturated substrate concentration, The Substrate Concentration is the number of moles of substrate per liter solution & The Dissociation Rate Constant is the ratio of reverse and forward rate constant.
How to calculate Initial Reaction Rate given Dissociation Rate Constant?
The Initial reaction rate given dissociation rate constant formula is defined as the relation with the maximum rate achieved by the system and the substrate concentration is calculated using Initial Reaction Rate given DRC = (Maximum Rate*Substrate Concentration)/(Dissociation Rate Constant+Substrate Concentration). To calculate Initial Reaction Rate given Dissociation Rate Constant, you need Maximum Rate (Vmax), Substrate Concentration (S) & Dissociation Rate Constant (KD). With our tool, you need to enter the respective value for Maximum Rate, Substrate Concentration & Dissociation Rate Constant and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
Let Others Know
Facebook
Twitter
Reddit
LinkedIn
Email
WhatsApp
Copied!