Reabsorption Rate of Drug Calculator

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✖Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time.ⓘ Renal Clearance [CL_r]			+10% -10%
✖Plasma Concentration is the concentration of the drug after administration and before the next dose is administered.ⓘ Plasma Concentration [C_p]			+10% -10%
✖Filtration Rate is the estimates of how much blood passes through the glomeruli each minute.ⓘ Filtration Rate [F_rate]			+10% -10%
✖Secretion Rate of Drug is the measure of the removal of drugs from the body, either as a metabolite or unchanged drug.ⓘ Secretion Rate of Drug [S_rate]			+10% -10%

✖Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma.ⓘ Reabsorption Rate of Drug [R_rate]

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Formula

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Reabsorption Rate of Drug

Formula

`"R"_{"rate"} = (("CL"_{"r"}*"C"_{"p"})+"F"_{"rate"}+"S"_{"rate"})`

Example

`"265224.4mL/min"=(("15.6mL/min"*"17mol/L")+"14mL/min"+"10.4mL/min")`

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Reabsorption Rate of Drug Solution

STEP 0: Pre-Calculation Summary

Formula Used

Reabsorption Rate of Drug = ((Renal Clearance*Plasma Concentration)+Filtration Rate+Secretion Rate of Drug)
R_rate = ((CL_r*C_p)+F_rate+S_rate)
This formula uses 5 Variables

Variables Used

Reabsorption Rate of Drug - (Measured in Cubic meter per second) - Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma.
Renal Clearance - (Measured in Cubic Meter per Second) - Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time.
Plasma Concentration - (Measured in Mole per Cubic Meter) - Plasma Concentration is the concentration of the drug after administration and before the next dose is administered.
Filtration Rate - (Measured in Cubic meter per second) - Filtration Rate is the estimates of how much blood passes through the glomeruli each minute.
Secretion Rate of Drug - (Measured in Cubic meter per second) - Secretion Rate of Drug is the measure of the removal of drugs from the body, either as a metabolite or unchanged drug.

STEP 1: Convert Input(s) to Base Unit

Renal Clearance: 15.6 Milliliter per Minute --> 2.6E-07 Cubic Meter per Second (Check conversion here)
Plasma Concentration: 17 Mole per Liter --> 17000 Mole per Cubic Meter (Check conversion here)
Filtration Rate: 14 Milliliter per Minute --> 2.33333333333333E-07 Cubic meter per second (Check conversion here)
Secretion Rate of Drug: 10.4 Milliliter per Minute --> 1.73333333333333E-07 Cubic meter per second (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

R_rate = ((CL_r*C_p)+F_rate+S_rate) --> ((2.6E-07*17000)+2.33333333333333E-07+1.73333333333333E-07)

Evaluating ... ...

R_rate = 0.00442040666666667

STEP 3: Convert Result to Output's Unit

0.00442040666666667 Cubic meter per second -->265224.4 Milliliter per Minute (Check conversion here)

FINAL ANSWER

265224.4 Milliliter per Minute <-- Reabsorption Rate of Drug

(Calculation completed in 00.004 seconds)

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Created by Soupayan banerjee

National University of Judicial Science (NUJS), Kolkata

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National Institute of Technology (NIT), Meghalaya

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< 14 Drug Content Calculators

Fraction of Drug Unbound in Tissue given Apparent Tissue Volume

Go Fraction Unbound in Tissue = (Fraction Unbound in Plasma*Apparent Tissue Volume)/(Volume of Distribution-Plasma Volume)

Secretion Rate of Drug

Go Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug)

Reabsorption Rate of Drug

Go Reabsorption Rate of Drug = ((Renal Clearance*Plasma Concentration)+Filtration Rate+Secretion Rate of Drug)

Filtration Rate of Drug

Go Filtration Rate = ((Renal Clearance*Plasma Concentration)+Reabsorption Rate of Drug-Secretion Rate of Drug)

Relative Bioavailability of Drug

Go Relative Bioavailability = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Dose Type A)

Drug Purity given Rate of Administration and Dosing Interval

Go Drug Purity = (Drug Rate of Administration*Dosing Interval)/(Administered Dose*Bioavailability)

Rate of Administration of Drug given Dosing Interval

Go Drug Rate of Administration = (Administered Dose*Bioavailability*Drug Purity)/Dosing Interval

Drug Purity given Administrative Dose and Effective Dose

Go Drug Purity = Effective Dose/(Administered Dose*Bioavailability)

Renal Clearance of Drug

Go Renal Clearance = Drug Amount Excreted Unchanged in Urine/Area Under Curve

Concentration of Drug given Rate of Infusion of Drug

Go Concentration of Drug = Rate of Infusion/Volume of Plasma Cleared

Rate of Infusion of Drug

Go Rate of Infusion = Volume of Plasma Cleared*Concentration of Drug

Absorption Half-Life of Drug

Go Absorption Half Life = ln(2)/Absorption Rate Constant

Drug Rate Entering Body

Go Absorption Rate Constant = ln(2)/Absorption Half Life

Apparent Volume of Drug Distribution

Go Volume of Distribution = Dose/Concentration of Drug

Reabsorption Rate of Drug Formula

Reabsorption Rate of Drug = ((Renal Clearance*Plasma Concentration)+Filtration Rate+Secretion Rate of Drug)
R_rate = ((CL_r*C_p)+F_rate+S_rate)

What is Pharmacokinetics?

Pharmacokinetics is currently defined as the study of the time course of drug absorption, distribution, metabolism, and excretion. Clinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient.

How to Calculate Reabsorption Rate of Drug?

Reabsorption Rate of Drug calculator uses Reabsorption Rate of Drug = ((Renal Clearance*Plasma Concentration)+Filtration Rate+Secretion Rate of Drug) to calculate the Reabsorption Rate of Drug, The Reabsorption Rate of Drug formula is defined as measure of movement of drug which is calculated using secretion, filtration rate , renal clearance and plasma concentration. Up to 99% of the fluid volume filtered at the glomerulus is reabsorbed. Reabsorption Rate of Drug is denoted by R_rate symbol.

How to calculate Reabsorption Rate of Drug using this online calculator? To use this online calculator for Reabsorption Rate of Drug, enter Renal Clearance (CL_r), Plasma Concentration (C_p), Filtration Rate (F_rate) & Secretion Rate of Drug (S_rate) and hit the calculate button. Here is how the Reabsorption Rate of Drug calculation can be explained with given input values -> 265224.4 = ((2.6E-07*17000)+2.33333333333333E-07+1.73333333333333E-07).

FAQ

What is Reabsorption Rate of Drug?

The Reabsorption Rate of Drug formula is defined as measure of movement of drug which is calculated using secretion, filtration rate , renal clearance and plasma concentration. Up to 99% of the fluid volume filtered at the glomerulus is reabsorbed and is represented as R_rate = ((CL_r*C_p)+F_rate+S_rate) or Reabsorption Rate of Drug = ((Renal Clearance*Plasma Concentration)+Filtration Rate+Secretion Rate of Drug). Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time, Plasma Concentration is the concentration of the drug after administration and before the next dose is administered, Filtration Rate is the estimates of how much blood passes through the glomeruli each minute & Secretion Rate of Drug is the measure of the removal of drugs from the body, either as a metabolite or unchanged drug.

How to calculate Reabsorption Rate of Drug?

The Reabsorption Rate of Drug formula is defined as measure of movement of drug which is calculated using secretion, filtration rate , renal clearance and plasma concentration. Up to 99% of the fluid volume filtered at the glomerulus is reabsorbed is calculated using Reabsorption Rate of Drug = ((Renal Clearance*Plasma Concentration)+Filtration Rate+Secretion Rate of Drug). To calculate Reabsorption Rate of Drug, you need Renal Clearance (CL_r), Plasma Concentration (C_p), Filtration Rate (F_rate) & Secretion Rate of Drug (S_rate). With our tool, you need to enter the respective value for Renal Clearance, Plasma Concentration, Filtration Rate & Secretion Rate of Drug and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

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