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Secretion Rate of Drug Solution

STEP 0: Pre-Calculation Summary
Formula Used
Secretion_rate_drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug)
Srate = (CLr*Cp)-(F rate)+(Rrate)
This formula uses 4 Variables
Variables Used
Renal Clearance - Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time. (Measured in Milliliter per Min)
Plasma Concentration - Plasma Concentration is the concentration of the drug after administration and before the next dose is administered. (Measured in Millimole per Liter)
Filtration Rate - Filtration Rate is the estimates of how much blood passes through the glomeruli each minute. (Measured in Milliliter per Minute)
Reabsorption Rate of Drug - Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma. (Measured in Milliliter per Minute)
STEP 1: Convert Input(s) to Base Unit
Renal Clearance: 10 Milliliter per Min --> 1.66666666666667E-07 Meter³ per Second (Check conversion here)
Plasma Concentration: 10 Millimole per Liter --> 10 Mole per Meter³ (Check conversion here)
Filtration Rate: 10 Milliliter per Minute --> 10 Milliliter per Minute No Conversion Required
Reabsorption Rate of Drug: 10 Milliliter per Minute --> 10 Milliliter per Minute No Conversion Required
STEP 2: Evaluate Formula
Substituting Input Values in Formula
Srate = (CLr*Cp)-(F rate)+(Rrate) --> (1.66666666666667E-07*10)-(10)+(10)
Evaluating ... ...
Srate = 1.66666666601145E-06
STEP 3: Convert Result to Output's Unit
1.66666666601145E-06 Milliliter per Minute --> No Conversion Required
FINAL ANSWER
1.66666666601145E-06 Milliliter per Minute <-- Secretion Rate of Drug
(Calculation completed in 00.005 seconds)

10+ Organic Chemistry>> Pharmacokinetics Calculators

Elimination half life given volume of plasma cleared
elimination_half_life = (ln(2)*Volume of Distribution)/Volume of plasma cleared Go
Elimination rate constant given area under curve
elimination_rate_constant = Dose/(Area under Curve*Volume of Distribution) Go
Elimination rate constant given volume of plasma cleared
elimination_rate_constant = Volume of plasma cleared/Volume of Distribution Go
Concentration of drug given rate of infusion of drug
concentration_of_drug = Rate of infusion/Volume of plasma cleared Go
Rate of infusion of drug
rate_of_infusion = Volume of plasma cleared*Concentration of drug Go
Elimination rate constant of drug
elimination_rate_constant = ln(2)/Elimination half life Go
Elimination half life of drug
elimination_half_life = ln(2)/Elimination rate constant Go
Rate at which drug enters into body
absorption_rate_constant = ln(2)/Absorption half life Go
Absorption half life of drug
absorption_half_life = ln(2)/Absorption rate constant Go
Apparent volume of drug distribution
volume_of_distribution = Dose/Concentration of drug Go

Secretion Rate of Drug Formula

Secretion_rate_drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug)
Srate = (CLr*Cp)-(F rate)+(Rrate)

What is Pharmacokinetics ?

Pharmacokinetics is currently defined as the study of the time course of drug absorption, distribution, metabolism, and excretion. Clinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient

How to Calculate Secretion Rate of Drug?

Secretion Rate of Drug calculator uses Secretion_rate_drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug) to calculate the Secretion Rate of Drug, The Secretion Rate of Drug formula is defined as excretion of some substance such as hydrogen ions, creatinine, and drugs which will be removed from the blood through the peritubular capillary network into the collecting duct. Secretion Rate of Drug is denoted by Srate symbol.

How to calculate Secretion Rate of Drug using this online calculator? To use this online calculator for Secretion Rate of Drug, enter Renal Clearance (CLr), Plasma Concentration (Cp), Filtration Rate (F rate) & Reabsorption Rate of Drug (Rrate) and hit the calculate button. Here is how the Secretion Rate of Drug calculation can be explained with given input values -> 1.667E-6 = (1.66666666666667E-07*10)-(10)+(10).

FAQ

What is Secretion Rate of Drug?
The Secretion Rate of Drug formula is defined as excretion of some substance such as hydrogen ions, creatinine, and drugs which will be removed from the blood through the peritubular capillary network into the collecting duct and is represented as Srate = (CLr*Cp)-(F rate)+(Rrate) or Secretion_rate_drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug). Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time, Plasma Concentration is the concentration of the drug after administration and before the next dose is administered, Filtration Rate is the estimates of how much blood passes through the glomeruli each minute & Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma.
How to calculate Secretion Rate of Drug?
The Secretion Rate of Drug formula is defined as excretion of some substance such as hydrogen ions, creatinine, and drugs which will be removed from the blood through the peritubular capillary network into the collecting duct is calculated using Secretion_rate_drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug). To calculate Secretion Rate of Drug, you need Renal Clearance (CLr), Plasma Concentration (Cp), Filtration Rate (F rate) & Reabsorption Rate of Drug (Rrate). With our tool, you need to enter the respective value for Renal Clearance, Plasma Concentration, Filtration Rate & Reabsorption Rate of Drug and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Secretion Rate of Drug?
In this formula, Secretion Rate of Drug uses Renal Clearance, Plasma Concentration, Filtration Rate & Reabsorption Rate of Drug. We can use 10 other way(s) to calculate the same, which is/are as follows -
  • volume_of_distribution = Dose/Concentration of drug
  • absorption_half_life = ln(2)/Absorption rate constant
  • absorption_rate_constant = ln(2)/Absorption half life
  • elimination_half_life = ln(2)/Elimination rate constant
  • elimination_rate_constant = ln(2)/Elimination half life
  • elimination_rate_constant = Volume of plasma cleared/Volume of Distribution
  • elimination_half_life = (ln(2)*Volume of Distribution)/Volume of plasma cleared
  • rate_of_infusion = Volume of plasma cleared*Concentration of drug
  • concentration_of_drug = Rate of infusion/Volume of plasma cleared
  • elimination_rate_constant = Dose/(Area under Curve*Volume of Distribution)
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