Area under Curve Given Average Plasma Concentration Calculator

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Area under curve

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✖Average Plasma Concentration is the average concentration of the drug after administration and before the next dose is administered.ⓘ Average Plasma Concentration [C_av]			+10% -10%
✖The Dosing Interval is the time between drug dose administrations.ⓘ Dosing Interval [Τ]			+10% -10%

✖Area under Curve (AUC) is the definite integral of a curve that describes the variation of a drug concentration in blood plasma as a function of time.ⓘ Area under Curve Given Average Plasma Concentration [AUC]

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Formula

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Area under Curve Given Average Plasma Concentration

Formula

`"AUC" = "C"_{"av"}*"Τ"`

Example

`"880mol*s/L"="20mol/L"*"44s"`

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Area under Curve Given Average Plasma Concentration Solution

STEP 0: Pre-Calculation Summary

Formula Used

Area Under Curve = Average Plasma Concentration*Dosing Interval
AUC = C_av*Τ
This formula uses 3 Variables

Variables Used

Area Under Curve - (Measured in Mole Second per Cubic Meter) - Area under Curve (AUC) is the definite integral of a curve that describes the variation of a drug concentration in blood plasma as a function of time.
Average Plasma Concentration - (Measured in Mole per Cubic Meter) - Average Plasma Concentration is the average concentration of the drug after administration and before the next dose is administered.
Dosing Interval - (Measured in Second) - The Dosing Interval is the time between drug dose administrations.

STEP 1: Convert Input(s) to Base Unit

Average Plasma Concentration: 20 Mole per Liter --> 20000 Mole per Cubic Meter (Check conversion here)
Dosing Interval: 44 Second --> 44 Second No Conversion Required

STEP 2: Evaluate Formula

Substituting Input Values in Formula

AUC = C_av*Τ --> 20000*44

Evaluating ... ...

AUC = 880000

STEP 3: Convert Result to Output's Unit

880000 Mole Second per Cubic Meter -->880 Mole Second per Liter (Check conversion here)

FINAL ANSWER

880 Mole Second per Liter <-- Area Under Curve

(Calculation completed in 00.004 seconds)

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Created by Prashant Singh

K J Somaiya College of science (K J Somaiya), Mumbai

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< 8 Area under curve Calculators

Area under Curve for Drug Administered Intravenous

Go Area under Curve Intravenous = (Area under Curve Non-Intravenous*Dose Intravenous)/(Bioavailability of Drug*Dose Non-Intravenous)

Area under Curve for Drug Administered Orally

Go Area under Curve Non-Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Dose Intravenous

Area under Curve of Drug for Dosage Type A

Go Area under curve Dosage A = (Relative Bioavailability*Area under curve Dosage B)*(Dose Type A/Dose Type B)

Area under Curve of Drug for Dosage Type B

Go Area under curve Dosage B = (Area under curve Dosage A/Relative Bioavailability)*(Dose Type B/Dose Type A)

Area under Curve given Dose and Volume of Distribution

Go Area Under Curve = Dose/(Volume of Distribution*Elimination Rate Constant)

Area under Curve Given Average Plasma Concentration

Go Area Under Curve = Average Plasma Concentration*Dosing Interval

Average Plasma Concentration given Area under Curve

Go Average Plasma Concentration = Area Under Curve/Dosing Interval

Area under Curve given Volume of Plasma Cleared

Go Area Under Curve = Dose/Volume of Plasma Cleared

Area under Curve Given Average Plasma Concentration Formula

Area Under Curve = Average Plasma Concentration*Dosing Interval
AUC = C_av*Τ

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Area under Curve Given Average Plasma Concentration?

Area under Curve Given Average Plasma Concentration calculator uses Area Under Curve = Average Plasma Concentration*Dosing Interval to calculate the Area Under Curve, The Area under Curve Given Average Plasma Concentration formula is defined as the product of time between drug dose administrations and average plasma concentration of drugs is given. Area Under Curve is denoted by AUC symbol.

How to calculate Area under Curve Given Average Plasma Concentration using this online calculator? To use this online calculator for Area under Curve Given Average Plasma Concentration, enter Average Plasma Concentration (C_av) & Dosing Interval (Τ) and hit the calculate button. Here is how the Area under Curve Given Average Plasma Concentration calculation can be explained with given input values -> 0.88 = 20000*44.

FAQ

What is Area under Curve Given Average Plasma Concentration?

The Area under Curve Given Average Plasma Concentration formula is defined as the product of time between drug dose administrations and average plasma concentration of drugs is given and is represented as AUC = C_av*Τ or Area Under Curve = Average Plasma Concentration*Dosing Interval. Average Plasma Concentration is the average concentration of the drug after administration and before the next dose is administered & The Dosing Interval is the time between drug dose administrations.

How to calculate Area under Curve Given Average Plasma Concentration?

The Area under Curve Given Average Plasma Concentration formula is defined as the product of time between drug dose administrations and average plasma concentration of drugs is given is calculated using Area Under Curve = Average Plasma Concentration*Dosing Interval. To calculate Area under Curve Given Average Plasma Concentration, you need Average Plasma Concentration (C_av) & Dosing Interval (Τ). With our tool, you need to enter the respective value for Average Plasma Concentration & Dosing Interval and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Area Under Curve?

In this formula, Area Under Curve uses Average Plasma Concentration & Dosing Interval. We can use 2 other way(s) to calculate the same, which is/are as follows -

Area Under Curve = Dose/Volume of Plasma Cleared
Area Under Curve = Dose/(Volume of Distribution*Elimination Rate Constant)

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