Area under Curve of Drug for Dosage Type B Calculator

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Area under curve

Bioavailability

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Elimination Rate Constant

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✖The Area under curve Dosage A is the integral of the concentration-time curve for A form of dosage.ⓘ Area under curve Dosage A [AUC_dosageA]			+10% -10%
✖Relative Bioavailability compares the bioavailability between two different dosage forms.ⓘ Relative Bioavailability [F_rel]			+10% -10%
✖Dose Type B is the amount of drug administered in B-type dosage form.ⓘ Dose Type B [D_B]			+10% -10%
✖Dose Type A is the amount of drug administered in A-type dosage form.ⓘ Dose Type A [D_A]			+10% -10%

✖The Area under curve Dosage B is the integral of the concentration-time curve for B form of dosage.ⓘ Area under Curve of Drug for Dosage Type B [AUC_dosageB]

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Area under Curve of Drug for Dosage Type B

Formula

`"AUC"_{"dosageB"} = ("AUC"_{"dosageA"}/"F"_{"rel"})*("D"_{"B"}/"D"_{"A"})`

Example

`"1.653623mol*s/L"=("1.141mol*s/L"/"0.9")*("15mol"/"11.5mol")`

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Area under Curve of Drug for Dosage Type B Solution

STEP 0: Pre-Calculation Summary

Formula Used

Area under curve Dosage B = (Area under curve Dosage A/Relative Bioavailability)*(Dose Type B/Dose Type A)
AUC_dosageB = (AUC_dosageA/F_rel)*(D_B/D_A)
This formula uses 5 Variables

Variables Used

Area under curve Dosage B - (Measured in Mole Second per Cubic Meter) - The Area under curve Dosage B is the integral of the concentration-time curve for B form of dosage.
Area under curve Dosage A - (Measured in Mole Second per Cubic Meter) - The Area under curve Dosage A is the integral of the concentration-time curve for A form of dosage.
Relative Bioavailability - Relative Bioavailability compares the bioavailability between two different dosage forms.
Dose Type B - (Measured in Mole) - Dose Type B is the amount of drug administered in B-type dosage form.
Dose Type A - (Measured in Mole) - Dose Type A is the amount of drug administered in A-type dosage form.

STEP 1: Convert Input(s) to Base Unit

Area under curve Dosage A: 1.141 Mole Second per Liter --> 1141 Mole Second per Cubic Meter (Check conversion here)
Relative Bioavailability: 0.9 --> No Conversion Required
Dose Type B: 15 Mole --> 15 Mole No Conversion Required
Dose Type A: 11.5 Mole --> 11.5 Mole No Conversion Required

STEP 2: Evaluate Formula

Substituting Input Values in Formula

AUC_dosageB = (AUC_dosageA/F_rel)*(D_B/D_A) --> (1141/0.9)*(15/11.5)

Evaluating ... ...

AUC_dosageB = 1653.6231884058

STEP 3: Convert Result to Output's Unit

1653.6231884058 Mole Second per Cubic Meter -->1.6536231884058 Mole Second per Liter (Check conversion here)

FINAL ANSWER

1.6536231884058 ≈ 1.653623 Mole Second per Liter <-- Area under curve Dosage B

(Calculation completed in 00.004 seconds)

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K J Somaiya College of science (K J Somaiya), Mumbai

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< 8 Area under curve Calculators

Area under Curve for Drug Administered Intravenous

Go Area under Curve Intravenous = (Area under Curve Non-Intravenous*Dose Intravenous)/(Bioavailability of Drug*Dose Non-Intravenous)

Area under Curve for Drug Administered Orally

Go Area under Curve Non-Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Dose Intravenous

Area under Curve of Drug for Dosage Type A

Go Area under curve Dosage A = (Relative Bioavailability*Area under curve Dosage B)*(Dose Type A/Dose Type B)

Area under Curve of Drug for Dosage Type B

Go Area under curve Dosage B = (Area under curve Dosage A/Relative Bioavailability)*(Dose Type B/Dose Type A)

Area under Curve given Dose and Volume of Distribution

Go Area Under Curve = Dose/(Volume of Distribution*Elimination Rate Constant)

Area under Curve Given Average Plasma Concentration

Go Area Under Curve = Average Plasma Concentration*Dosing Interval

Average Plasma Concentration given Area under Curve

Go Average Plasma Concentration = Area Under Curve/Dosing Interval

Area under Curve given Volume of Plasma Cleared

Go Area Under Curve = Dose/Volume of Plasma Cleared

Area under Curve of Drug for Dosage Type B Formula

Area under curve Dosage B = (Area under curve Dosage A/Relative Bioavailability)*(Dose Type B/Dose Type A)
AUC_dosageB = (AUC_dosageA/F_rel)*(D_B/D_A)

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Area under Curve of Drug for Dosage Type B?

Area under Curve of Drug for Dosage Type B calculator uses Area under curve Dosage B = (Area under curve Dosage A/Relative Bioavailability)*(Dose Type B/Dose Type A) to calculate the Area under curve Dosage B, The Area under Curve of Drug for Dosage Type B formula is defined as the comparison of the bioavailability between two different dosage forms. The relative AUCs are used to make this comparison and relative doses are used to normalize the calculation. Area under curve Dosage B is denoted by AUC_dosageB symbol.

How to calculate Area under Curve of Drug for Dosage Type B using this online calculator? To use this online calculator for Area under Curve of Drug for Dosage Type B, enter Area under curve Dosage A (AUC_dosageA), Relative Bioavailability (F_rel), Dose Type B (D_B) & Dose Type A (D_A) and hit the calculate button. Here is how the Area under Curve of Drug for Dosage Type B calculation can be explained with given input values -> 0.001654 = (1141/0.9)*(15/11.5).

FAQ

What is Area under Curve of Drug for Dosage Type B?

The Area under Curve of Drug for Dosage Type B formula is defined as the comparison of the bioavailability between two different dosage forms. The relative AUCs are used to make this comparison and relative doses are used to normalize the calculation and is represented as AUC_dosageB = (AUC_dosageA/F_rel)*(D_B/D_A) or Area under curve Dosage B = (Area under curve Dosage A/Relative Bioavailability)*(Dose Type B/Dose Type A). The Area under curve Dosage A is the integral of the concentration-time curve for A form of dosage, Relative Bioavailability compares the bioavailability between two different dosage forms, Dose Type B is the amount of drug administered in B-type dosage form & Dose Type A is the amount of drug administered in A-type dosage form.

How to calculate Area under Curve of Drug for Dosage Type B?

The Area under Curve of Drug for Dosage Type B formula is defined as the comparison of the bioavailability between two different dosage forms. The relative AUCs are used to make this comparison and relative doses are used to normalize the calculation is calculated using Area under curve Dosage B = (Area under curve Dosage A/Relative Bioavailability)*(Dose Type B/Dose Type A). To calculate Area under Curve of Drug for Dosage Type B, you need Area under curve Dosage A (AUC_dosageA), Relative Bioavailability (F_rel), Dose Type B (D_B) & Dose Type A (D_A). With our tool, you need to enter the respective value for Area under curve Dosage A, Relative Bioavailability, Dose Type B & Dose Type A and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

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