## Concentration of Drug given Rate of Infusion of Drug Solution

STEP 0: Pre-Calculation Summary
Formula Used
Concentration of Drug = Rate of Infusion/Volume of Plasma Cleared
Css = kin/CL
This formula uses 3 Variables
Variables Used
Concentration of Drug - (Measured in Mole per Cubic Meter) - Concentration of Drug is the amount of the drug in a given volume of plasma.
Rate of Infusion - (Measured in Mole per Second) - The Rate of Infusion is defined as the rate required to balance elimination.
Volume of Plasma Cleared - (Measured in Cubic Meter per Second) - The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.
STEP 1: Convert Input(s) to Base Unit
Rate of Infusion: 55 Mole per Second --> 55 Mole per Second No Conversion Required
Volume of Plasma Cleared: 0.48 Liter per Second --> 0.00048 Cubic Meter per Second (Check conversion here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
Css = kin/CL --> 55/0.00048
Evaluating ... ...
Css = 114583.333333333
STEP 3: Convert Result to Output's Unit
114583.333333333 Mole per Cubic Meter -->114.583333333333 Mole per Liter (Check conversion here)
114.583333333333 114.5833 Mole per Liter <-- Concentration of Drug
(Calculation completed in 00.004 seconds)
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K J Somaiya College of science (K J Somaiya), Mumbai
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## < 21 Drug Content Calculators

Saponification value
Saponification Value = Molecular weight of KOH*(Volume of blank-Volume of Actual solution)*Normality of solution/Weight of sample taken
Fraction of Drug Unbound in Tissue given Apparent Tissue Volume
Fraction Unbound in Tissue = (Fraction Unbound in Plasma*Apparent Tissue Volume)/(Volume of Distribution-Plasma Volume)
Secretion Rate of Drug
Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug)
Reabsorption Rate of Drug
Reabsorption Rate of Drug = ((Renal Clearance*Plasma Concentration)+Filtration Rate+Secretion Rate of Drug)
Filtration Rate of Drug
Filtration Rate = ((Renal Clearance*Plasma Concentration)+Reabsorption Rate of Drug-Secretion Rate of Drug)
Relative Bioavailability of Drug
Relative Bioavailability = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Dose Type A)
Acid Value of KOH
Acid Value = Molecular weight of KOH*Volume of solution koh*Normality of solution/Weight of sample taken
Drug Purity given Rate of Administration and Dosing Interval
Rate of Administration of Drug given Dosing Interval
Drug Purity given Administrative Dose and Effective Dose
Drug Purity = Effective Dose/(Administered Dose*Bioavailability)
Drug Loading Efficiency = Weight of drug in nanoparticles/Weight of the Nanoparticles*100
Encapsulation Efficiency
Encapsulation Efficiency = Weight of drug in nanoparticles/Weight of feeding drug*100
Renal Clearance of Drug
Renal Clearance = Drug Amount Excreted Unchanged in Urine/Area Under Curve
Concentration of Drug given Rate of Infusion of Drug
Concentration of Drug = Rate of Infusion/Volume of Plasma Cleared
Rate of Infusion of Drug
Rate of Infusion = Volume of Plasma Cleared*Concentration of Drug
Therapeutic Index
Therapeutic Index = Median Lethal Dose/Median Effective Dose
Absorption Half-Life of Drug
Absorption Half Life = ln(2)/Absorption Rate Constant
Drug Rate Entering Body
Absorption Rate Constant = ln(2)/Absorption Half Life
Apparent Volume of Drug Distribution
Volume of Distribution = Dose/Concentration of Drug
Tablet Dosage
Number of tablet = Desired dosage/Stock strength
Easter Value
Easter Value = Saponification Value-Acid Value

## Concentration of Drug given Rate of Infusion of Drug Formula

Concentration of Drug = Rate of Infusion/Volume of Plasma Cleared
Css = kin/CL

## What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

## How to Calculate Concentration of Drug given Rate of Infusion of Drug?

Concentration of Drug given Rate of Infusion of Drug calculator uses Concentration of Drug = Rate of Infusion/Volume of Plasma Cleared to calculate the Concentration of Drug, The Concentration of drug given rate of infusion of drug formula is defined as the ratio of the rate of infusion required to balance elimination to the amount of drug in a given volume of plasma. Concentration of Drug is denoted by Css symbol.

How to calculate Concentration of Drug given Rate of Infusion of Drug using this online calculator? To use this online calculator for Concentration of Drug given Rate of Infusion of Drug, enter Rate of Infusion (kin) & Volume of Plasma Cleared (CL) and hit the calculate button. Here is how the Concentration of Drug given Rate of Infusion of Drug calculation can be explained with given input values -> 0.114583 = 55/0.00048.

### FAQ

What is Concentration of Drug given Rate of Infusion of Drug?
The Concentration of drug given rate of infusion of drug formula is defined as the ratio of the rate of infusion required to balance elimination to the amount of drug in a given volume of plasma and is represented as Css = kin/CL or Concentration of Drug = Rate of Infusion/Volume of Plasma Cleared. The Rate of Infusion is defined as the rate required to balance elimination & The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.
How to calculate Concentration of Drug given Rate of Infusion of Drug?
The Concentration of drug given rate of infusion of drug formula is defined as the ratio of the rate of infusion required to balance elimination to the amount of drug in a given volume of plasma is calculated using Concentration of Drug = Rate of Infusion/Volume of Plasma Cleared. To calculate Concentration of Drug given Rate of Infusion of Drug, you need Rate of Infusion (kin) & Volume of Plasma Cleared (CL). With our tool, you need to enter the respective value for Rate of Infusion & Volume of Plasma Cleared and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
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