## Total Clearance of Body Solution

STEP 0: Pre-Calculation Summary
Formula Used
Total Clearance = Hepatic Clearance+Renal Clearance for Total+Pulmonary Clearance+Other Clearance
CLtotal = CLhepatic+CLrenal+CLpulmonary+CLother
This formula uses 5 Variables
Variables Used
Total Clearance - (Measured in Cubic Meter per Second) - The Total Clearance is the total clearance of a drug from the body. It is a measure of how quickly the drug is eliminated from the body.
Hepatic Clearance - (Measured in Cubic Meter per Second) - The Hepatic Clearance is the clearance of a drug by the liver. The liver is a major organ for drug metabolism, and it is responsible for breaking down and eliminating many drugs from the body.
Renal Clearance for Total - (Measured in Cubic Meter per Second) - The Renal Clearance for Total is the clearance of a drug by the kidneys. The kidneys are responsible for filtering out drugs from the blood, and they are a major route of drug elimination.
Pulmonary Clearance - (Measured in Cubic Meter per Second) - The Pulmonary Clearance is the clearance of a drug by the lungs. The lungs are responsible for exchanging gases in the blood, and they can also eliminate some drugs from the body.
Other Clearance - (Measured in Cubic Meter per Second) - The Other Clearance is the clearance of a drug by other organs or tissues. There are organs and tissues that can contribute to the clearance of drugs, such as the gut, the brain, and the skin.
STEP 1: Convert Input(s) to Base Unit
Hepatic Clearance: 1.5 Liter per hour --> 4.16666666666667E-07 Cubic Meter per Second (Check conversion here)
Renal Clearance for Total: 2 Liter per hour --> 5.55555555555556E-07 Cubic Meter per Second (Check conversion here)
Pulmonary Clearance: 1.5 Liter per hour --> 4.16666666666667E-07 Cubic Meter per Second (Check conversion here)
Other Clearance: 0.2 Liter per hour --> 5.55555555555556E-08 Cubic Meter per Second (Check conversion here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
CLtotal = CLhepatic+CLrenal+CLpulmonary+CLother --> 4.16666666666667E-07+5.55555555555556E-07+4.16666666666667E-07+5.55555555555556E-08
Evaluating ... ...
CLtotal = 1.44444444444445E-06
STEP 3: Convert Result to Output's Unit
1.44444444444445E-06 Cubic Meter per Second -->5.2 Liter per hour (Check conversion here)
5.2 Liter per hour <-- Total Clearance
(Calculation completed in 00.004 seconds)
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## < 6 Elimination Rate Constant Calculators

Total Clearance of Body
Total Clearance = Hepatic Clearance+Renal Clearance for Total+Pulmonary Clearance+Other Clearance
Elimination Half Life given Volume of Plasma Cleared
Elimination Half Life = (ln(2)*Volume of Distribution)/Volume of Plasma Cleared
Elimination Rate Constant given Area under Curve
Elimination Rate Constant = Dose/(Area Under Curve*Volume of Distribution)
Elimination Rate Constant given Volume of Plasma Cleared
Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution
Elimination Rate Constant of Drug
Elimination Rate Constant = ln(2)/Elimination Half Life
Elimination Half Life of Drug
Elimination Half Life = ln(2)/Elimination Rate Constant

## Total Clearance of Body Formula

Total Clearance = Hepatic Clearance+Renal Clearance for Total+Pulmonary Clearance+Other Clearance
CLtotal = CLhepatic+CLrenal+CLpulmonary+CLother

## What are main clearance organs?

CLhepatic: This is the clearance of a drug by the liver. The liver is a major organ for drug metabolism, and it is responsible for breaking down and eliminating many drugs from the body.
CLrenal: This is the clearance of a drug by the kidneys. The kidneys are responsible for filtering out drugs from the blood, and they are a major route of drug elimination.
CLpulmonary: This is the clearance of a drug by the lungs. The lungs are responsible for exchanging gases in the blood, and they can also eliminate some drugs from the body.
CLother: This is the clearance of a drug by other organs or tissues. There are a number of other organs and tissues that can contribute to the clearance of drugs, such as the gut, the brain, and the skin.

## How to Calculate Total Clearance of Body?

Total Clearance of Body calculator uses Total Clearance = Hepatic Clearance+Renal Clearance for Total+Pulmonary Clearance+Other Clearance to calculate the Total Clearance, The Total Clearance of Body formula is defined as is the total clearance of a drug from the body. It is a measure of how quickly the drug is eliminated from the body. Total Clearance is denoted by CLtotal symbol.

How to calculate Total Clearance of Body using this online calculator? To use this online calculator for Total Clearance of Body, enter Hepatic Clearance (CLhepatic), Renal Clearance for Total (CLrenal), Pulmonary Clearance (CLpulmonary) & Other Clearance (CLother) and hit the calculate button. Here is how the Total Clearance of Body calculation can be explained with given input values -> 1.9E+7 = 4.16666666666667E-07+5.55555555555556E-07+4.16666666666667E-07+5.55555555555556E-08.

### FAQ

What is Total Clearance of Body?
The Total Clearance of Body formula is defined as is the total clearance of a drug from the body. It is a measure of how quickly the drug is eliminated from the body and is represented as CLtotal = CLhepatic+CLrenal+CLpulmonary+CLother or Total Clearance = Hepatic Clearance+Renal Clearance for Total+Pulmonary Clearance+Other Clearance. The Hepatic Clearance is the clearance of a drug by the liver. The liver is a major organ for drug metabolism, and it is responsible for breaking down and eliminating many drugs from the body, The Renal Clearance for Total is the clearance of a drug by the kidneys. The kidneys are responsible for filtering out drugs from the blood, and they are a major route of drug elimination, The Pulmonary Clearance is the clearance of a drug by the lungs. The lungs are responsible for exchanging gases in the blood, and they can also eliminate some drugs from the body & The Other Clearance is the clearance of a drug by other organs or tissues. There are organs and tissues that can contribute to the clearance of drugs, such as the gut, the brain, and the skin.
How to calculate Total Clearance of Body?
The Total Clearance of Body formula is defined as is the total clearance of a drug from the body. It is a measure of how quickly the drug is eliminated from the body is calculated using Total Clearance = Hepatic Clearance+Renal Clearance for Total+Pulmonary Clearance+Other Clearance. To calculate Total Clearance of Body, you need Hepatic Clearance (CLhepatic), Renal Clearance for Total (CLrenal), Pulmonary Clearance (CLpulmonary) & Other Clearance (CLother). With our tool, you need to enter the respective value for Hepatic Clearance, Renal Clearance for Total, Pulmonary Clearance & Other Clearance and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
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