Drug Purity given Administrative Dose and Effective Dose Calculator

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✖The Effective Dose is a dose or concentration of a drug that produces a biological response.ⓘ Effective Dose [D_e]			+10% -10%
✖Administered Dose is the amount of drug administered for a pharmacological response.ⓘ Administered Dose [D_a]			+10% -10%
✖The Bioavailability is the systemically available fraction of a drug.ⓘ Bioavailability [B]			+10% -10%

✖The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.ⓘ Drug Purity given Administrative Dose and Effective Dose [Q]

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Formula

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Drug Purity given Administrative Dose and Effective Dose

Formula

`"Q" = "D"_{"e"}/("D"_{"a"}*"B")`

Example

`"0.125714"="5.5µg"/("3.5µg"*"12.5")`

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Drug Purity given Administrative Dose and Effective Dose Solution

STEP 0: Pre-Calculation Summary

Formula Used

Drug Purity = Effective Dose/(Administered Dose*Bioavailability)
Q = D_e/(D_a*B)
This formula uses 4 Variables

Variables Used

Drug Purity - The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.
Effective Dose - (Measured in Kilogram) - The Effective Dose is a dose or concentration of a drug that produces a biological response.
Administered Dose - (Measured in Kilogram) - Administered Dose is the amount of drug administered for a pharmacological response.
Bioavailability - The Bioavailability is the systemically available fraction of a drug.

STEP 1: Convert Input(s) to Base Unit

Effective Dose: 5.5 Microgram --> 5.5E-09 Kilogram (Check conversion here)
Administered Dose: 3.5 Microgram --> 3.5E-09 Kilogram (Check conversion here)
Bioavailability: 12.5 --> No Conversion Required

STEP 2: Evaluate Formula

Substituting Input Values in Formula

Q = D_e/(D_a*B) --> 5.5E-09/(3.5E-09*12.5)

Evaluating ... ...

Q = 0.125714285714286

STEP 3: Convert Result to Output's Unit

0.125714285714286 --> No Conversion Required

FINAL ANSWER

0.125714285714286 ≈ 0.125714 <-- Drug Purity

(Calculation completed in 00.004 seconds)

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K J Somaiya College of science (K J Somaiya), Mumbai

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Go Saponification Value = Molecular weight of KOH*(Volume of blank-Volume of Actual solution)*Normality of solution/Weight of sample taken

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Go Fraction Unbound in Tissue = (Fraction Unbound in Plasma*Apparent Tissue Volume)/(Volume of Distribution-Plasma Volume)

Secretion Rate of Drug

Go Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug)

Reabsorption Rate of Drug

Go Reabsorption Rate of Drug = ((Renal Clearance*Plasma Concentration)+Filtration Rate+Secretion Rate of Drug)

Filtration Rate of Drug

Go Filtration Rate = ((Renal Clearance*Plasma Concentration)+Reabsorption Rate of Drug-Secretion Rate of Drug)

Relative Bioavailability of Drug

Go Relative Bioavailability = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Dose Type A)

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Go Acid Value = Molecular weight of KOH*Volume of solution koh*Normality of solution/Weight of sample taken

Drug Purity given Rate of Administration and Dosing Interval

Go Drug Purity = (Drug Rate*Dosing Interval)/(Administered Dose*Bioavailability)

Rate of Administration of Drug given Dosing Interval

Go Drug Rate = (Administered Dose*Bioavailability*Drug Purity)/Dosing Interval

Drug Purity given Administrative Dose and Effective Dose

Go Drug Purity = Effective Dose/(Administered Dose*Bioavailability)

Drug Loading Efficiency

Go Drug Loading Efficiency = Weight of drug in nanoparticles/Weight of the Nanoparticles*100

Encapsulation Efficiency

Go Encapsulation Efficiency = Weight of drug in nanoparticles/Weight of feeding drug*100

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Go Renal Clearance = Drug Amount Excreted Unchanged in Urine/Area Under Curve

Concentration of Drug given Rate of Infusion of Drug

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Go Absorption Rate Constant = ln(2)/Absorption Half Life

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Go Number of tablet = Desired dosage/Stock strength

Easter Value

Go Easter Value = Saponification Value-Acid Value

Drug Purity given Administrative Dose and Effective Dose Formula

Drug Purity = Effective Dose/(Administered Dose*Bioavailability)
Q = D_e/(D_a*B)

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Drug Purity given Administrative Dose and Effective Dose?

Drug Purity given Administrative Dose and Effective Dose calculator uses Drug Purity = Effective Dose/(Administered Dose*Bioavailability) to calculate the Drug Purity, The Drug purity given Administrative dose and Effective dose formula is defined as the ratio of the effective dose to the administered dose and bioavailability of the particular drug. Drug Purity is denoted by Q symbol.

How to calculate Drug Purity given Administrative Dose and Effective Dose using this online calculator? To use this online calculator for Drug Purity given Administrative Dose and Effective Dose, enter Effective Dose (D_e), Administered Dose (D_a) & Bioavailability (B) and hit the calculate button. Here is how the Drug Purity given Administrative Dose and Effective Dose calculation can be explained with given input values -> 0.125714 = 5.5E-09/(3.5E-09*12.5).

FAQ

What is Drug Purity given Administrative Dose and Effective Dose?

The Drug purity given Administrative dose and Effective dose formula is defined as the ratio of the effective dose to the administered dose and bioavailability of the particular drug and is represented as Q = D_e/(D_a*B) or Drug Purity = Effective Dose/(Administered Dose*Bioavailability). The Effective Dose is a dose or concentration of a drug that produces a biological response, Administered Dose is the amount of drug administered for a pharmacological response & The Bioavailability is the systemically available fraction of a drug.

How to calculate Drug Purity given Administrative Dose and Effective Dose?

The Drug purity given Administrative dose and Effective dose formula is defined as the ratio of the effective dose to the administered dose and bioavailability of the particular drug is calculated using Drug Purity = Effective Dose/(Administered Dose*Bioavailability). To calculate Drug Purity given Administrative Dose and Effective Dose, you need Effective Dose (D_e), Administered Dose (D_a) & Bioavailability (B). With our tool, you need to enter the respective value for Effective Dose, Administered Dose & Bioavailability and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Drug Purity?

In this formula, Drug Purity uses Effective Dose, Administered Dose & Bioavailability. We can use 1 other way(s) to calculate the same, which is/are as follows -

Drug Purity = (Drug Rate*Dosing Interval)/(Administered Dose*Bioavailability)

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